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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
Testing for CAS 55184-72-0 is covered by tests with CAS 848588-96-5. Both substances are very similar since they differ mainly in the share of C13 (CAS 848588-96-5 C13> 80%; CAS 55184-72-0 > 95%). Hence, read across from CAS 848588-96-5 (source) to CAS 55184-72-0 (target) is considered as appropriate for both substances.
Reason / purpose:
read-across source
Key result
Medium:
n-octanol
Solubility:
> 500 g/L
Temp.:
20 °C
Test substance stable:
yes

The following aliquots of test item were added to 2 mL of n-octanol and stirred slowly for 10 minutes:

 

 

Aliquot

Cumulative weighed sample (g) /Observation

A

0.02 clear solution

B

0.1 clear solution

C

0.5 clear solution

D

1.0 clear solution, increasing viscosity

E

2.0 jelly like, highly viscous

 

 

While being added to the solvent, clear solutions with increasing viscosity were being formed, resulting in a gel after the addition of 2.0 g test item to 2 ml n-octanol.

Testing for CAS 55184-72-0 is covered by tests with CAS 848588-96-5. Both substances are very similar since they differ mainly in the share of C13 (CAS 848588-96-5 C13> 80%; CAS 55184-72-0 > 95%). Hence, read across from CAS 848588-96-5 (source) to CAS 55184-72-0 (target) is considered as appropriate for both substances.

Executive summary:

In the non GLP Klimisch 1 key study from Frischmann (2013), the n-octanol solubility of Sodium bis(C11-14-isoalkyl, C13-rich) sulfosuccinate was determined according to OECD 105 with the exception that n-octanol instead of water was used.

The octanol solubility of Sodium bis(C11-14-isoalkyl, C13-rich) sulfosuccinate is greater than 500 g/L. Sodium bis(C11-14-isoalkyl, C13-rich) sulfosuccinate is miscible with octanol in any proportion. With increasing amount of test item a gel is formed.

Testing for CAS 55184-72-0 is covered by tests with CAS 848588-96-5. Both substances are very similar since they differ mainly in the share of C13 (CAS 848588-96-5 C13> 80%; CAS 55184-72-0 > 95%). Hence, read across from CAS 848588-96-5 (source) to CAS 55184-72-0 (target) is considered as appropriate for both substances.

The results of this study are considered relevant and reliable for the risk assessment.

Description of key information

Key value for chemical safety assessment

Additional information

In the non GLP Klimisch 1 key study from Frischmann (2013), the n-octanol solubility of Sodium bis(C11-14-isoalkyl, C13-rich) sulfosuccinate was determined according to OECD 105 with the exception that n-octanol instead of water was used.

The octanol solubility of Sodium bis(C11-14-isoalkyl, C13-rich) sulfosuccinate is greater than 500 g/L. Sodium bis(C11-14-isoalkyl, C13-rich) sulfosuccinate is miscible with octanol in any proportion. With increasing amount of test item a gel is formed.

The results of this study are considered relevant and reliable for the risk assessment.