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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

A respiration inhibition study was performed to assess the effect of nopyl acetate on STP microorganisms according to OECD Guideline No 209. 
The 3h-EC50 of nopyl acetate for inhibition of respiration of activated sludge is 190 mg/L.
The 3h-EC10 of nopyl acetate for inhibition of respiration of activated sludge is 40 mg/L.
Therefore nopyl acetate is considered not harmful to activated sludge.

Key value for chemical safety assessment

EC50 for microorganisms:
190 mg/L
EC10 or NOEC for microorganisms:
40 mg/L

Additional information

Key study conducted according to OECD 209 Guideline under GLP without deviation.

Nopyl acetate was tested at nominal concentrations of 19.8, 39.3, 78.6, 157.1, 314.2, 628.5, and 1257.0 mg/L and the inoculum (microbial source) was activated sludge of a predominantly domestic sewage. The validity criteria were fulfilled and the observed 3h-EC50 and 3h-EC10 values can be used for chemical safety assessment.