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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

An algal toxicity study was performed in accordance with OECD Guideline No 201.
The 72h-ErC50 of nopyl acetate for freshwater algae is 7.11 mg/L.
The 72h-ErC10 of nopyl acetate for freshwater algae is 2.59 mg/L.
Based on the results of this study, nopyl acetate is classified:
- dangerous for the environment according to Directive 67/548/EEC "R51/53: toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment"
- and hazardous to the aquatic environment under Regulation (EC) No 1272/2008 (CLP) - Category Chronic 2.

Key value for chemical safety assessment

EC50 for freshwater algae:
7.11 mg/L
EC10 or NOEC for freshwater algae:
2.59 mg/L

Additional information

Key study conducted according to OECD 201 and EU C3 Guidelines under GLP without deviation.

Algae cultures (Pseudokirchneriella subcapitata) were exposed to nopyl acetate at nominal concentrations of 1.0, 1.8, 3.3, 6.0, 11 and 20 mg/L over a test period of 72 hours (static test). Concentrations were measured at the start of the study and daily until the end of the test. The concentrations of the test item were not satisfactorily maintained within ± 20% of the initial concentrations throughout the test, thus the EC50 were based on the geometric mean of the measured concentrations in abiotic replicates. The 72h-ErC50 and the 72h-ErC10 obtained in this study can be used as key values for chemical safety assessment.