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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

An acute aquatic toxicity study was performed on zebrafish (Danio rerio) in accordance with OECD Guideline No 203.
The 96h-LC50 of nopyl acetate for freshwater fish is 11.44 mg/L.

Key value for chemical safety assessment

LC50 for freshwater fish:
11.44 mg/L

Additional information

Key study conducted according to OECD 203 Guideline and GLP without deviation.

Fish (Danio rerio) were exposed to nopyl acetate at nominal concentrations of 1.0, 1.8, 3.3, 6.0, 11 and 20 mg/L over a test period of 96 hours (semi-static test, daily renewal). Concentrations were measured at the start of the study and daily until the end of the test. The concentrations of the test item were not satisfactorily maintained within ± 20% of the initial concentrations throughout the test, thus the LC50 were based on the geometric mean of the measured concentrations. The 96h-LC50 determined in this study can be used as key value for chemical safety assessment.