Registration Dossier

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vitro / ex vivo
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion

Conclusions:
The components of highly inverted invert sugar (sucrose, glucose and fructose) are all included in Annex IV of the REACH regulation, indicating that sufficient information is known about these substances that they are considered to cause minimum risk because of their intrinsic properties. Therefore, a skin irritation study for highly inverted invert sugar is not necessary.
Executive summary:

The components of highly inverted invert sugar (sucrose, glucose and fructose) are all included in Annex IV of the REACH regulation, indicating that sufficient information is known about these substances that they are considered to cause minimum risk because of their intrinsic properties. Therefore, a skin irritation study for highly inverted invert sugar is not necessary.