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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From July 29 to September 6, 2005
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. No deviation affected the quality of the study. The substance is considered to be adequately characterised with its purity. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
UK GLP Compliance Programme (inspected on April 12, 2005/ signed on June 01, 2005)
Type of method:
effusion method: vapour pressure balance
Key result
Temp.:
25 °C
Vapour pressure:
0.098 Pa

Table 4.6/1: Vapour pressure - results

 

 

Run 1

Run 2

Correlation

-0.9970

-0.9979

Slope

-5676

-6001

Intercept

18.03

19.11

Vp (Pa) at 25°C

9.9 x 10-2

9.6 x 10-2

 

The two runs gave a mean vapour pressure value at 25 °C of 9.8 x 10-2 Pa.

Conclusions:
Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).
Executive summary:

The vapour pressure of the test substance was measured according to OECD 104/EU A4 guideline, effusion method: vapour pressure balance.

Two definitive runs were performed between temperatures of 26.0 and 36.5 °C (n=6). Vapor pressure at 25 °C was extrapolated from the regression.

The vapour pressure was determined to be 9.8 x 10-2 Pa at 25 °C.

Description of key information

Low volatility.

Key value for chemical safety assessment

Vapour pressure:
0.098 Pa
at the temperature of:
25 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Therefore, it is considered as a key study. The result is retained as key data.