Registration Dossier

Ecotoxicological information

Toxicity to soil microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

The terrestrial chemical safety assessment has been conducted using the Equilibrium Partitioning method (EQPM)*.

It is recognised that the aquatic PNEC used in the EQPM does not take into account any indicator for effects in aquatic microorganisms. However, a reliability 4 bacterial respiration inhibition test with DTPMP records an EC50 value of >2500 mg/l (nominal, Grohmann and Horstmann, 1989) with Photobacterium phosphoreum and studies with the related substances ATMP and HEDP indicate a lack of inhibition at ca. 200 mg/l in activated sludge (both Henkel, 1972, see Section 6.1.7).

These results show a similar level of effect to that observed in the lowest reliable short-term aquatic toxicity study with fish, where a 96-h LC50 value of 216 mg active acid/L with Salmo gairdneri was determined (ABC, 1980).

Therefore it is unlikely that the PNECterrestrial based on aquatic ecotoxicity test results would not be protective for terrestrial microorganisms.

The chemical safety assessment using EQPM does not suggest any unacceptable risks for the terrestrial compartment.

*A reproductive toxicity study with earthworms (OECD TG 222) is proposed, which may affect the current RCRs.