Registration Dossier

Physical & Chemical properties

Dissociation constant

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

DTPMP acid has ten ionisable groups.

Key value for chemical safety assessment

Additional information

Ten dissociation constant values as listed below are reported in secondary literature which is considered reliable.

1.03 
2.08 
3.11
4.15 
5.19 
6.23 
7.23 
8.30 
1.18 
12.58

Eight of the ten pKa values were determined in a second reliable study (Martell 1968) and are listed below.

pKa3 = 2.8
pKa4 = 4.45
pKa5 = 5.5
pKa6 = 6.38
pKa7 = 7.17
pKa8 = 8.15
pKa9 = 10.1
pKa10 = 12.04

The two sources are considered to be reliable and are used as weight of evidence.