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Environmental fate & pathways

Biodegradation in water: screening tests

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Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
20-01-2003 to 24-03-2003
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reference:
Composition 0
Qualifier:
according to
Guideline:
EU Method C.4-B (Determination of the "Ready" Biodegradability - Modified OECD Screening Test)
Qualifier:
according to
Guideline:
OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
GLP compliance:
yes (incl. certificate)
Test material information:
Composition 1
Oxygen conditions:
aerobic
Inoculum or test system:
sewage, domestic (adaptation not specified)
Duration of test (contact time):
28 d
Initial conc.:
20 mg/L
Based on:
DOC
Parameter followed for biodegradation estimation:
DOC removal
Details on study design:
TEST CONDITIONS
- Test temperature: 22 +/+ 2°C
- Continuous darkness: yes

TEST SYSTEM
- Number of culture flasks/concentration: 2
- Measuring equipment: DOC-analyser Shimadzu TOC 505 A

SAMPLING
- Sampling frequency: 0h, 7d, 14d, 21d, 27d and 28d

CONTROL AND BLANK SYSTEM
- Inoculum blank: mineral medium containing only inoculum
- Procedure control: refernce chemical sodium benzoate (20mg DOC/L)
Reference substance:
benzoic acid, sodium salt
Parameter:
% degradation (DOC removal)
Value:
0
Sampling time:
7 d
Parameter:
% degradation (DOC removal)
Value:
0
Sampling time:
14 d
Parameter:
% degradation (DOC removal)
Value:
7
Sampling time:
21 d
Parameter:
% degradation (DOC removal)
Value:
9
Sampling time:
27 d
Key result
Parameter:
% degradation (DOC removal)
Value:
14
Sampling time:
28 d
Validity criteria fulfilled:
yes
Remarks:
The optional toxicity control was not performed. The validity of the study is not adversely affected.
Interpretation of results:
not readily biodegradable
Conclusions:
The biodegradation of the test item was determined in a GLP study according to OECD 301E. Within 28 days, a degradation of 14% was determined.
The test item has to be clasified as "Not Readily Biodegradable" under the conditions of the test.
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: read across from Klimisch 1 guideline study
Justification for type of information:
This endpoint is read across from Potassium-1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonate, CAS 29420-49-3. A justification is attached to section 13 of this dossier.
Reason / purpose:
read-across source
Related information:
Composition 1
Test material information:
Composition 1
Key result
Parameter:
% degradation (DOC removal)
Value:
14
Sampling time:
28 d
Remarks on result:
other: result for 1-butanesulfonic acid, 1,1,2,2,3,3,4,4,4-nonalfluoropotassium salt (CAS 29420-49-3)
Validity criteria fulfilled:
yes
Interpretation of results:
not readily biodegradable
Conclusions:
The biodegradability of the test item was derived from the source substance 1-butanesulfonic acid, 1,1,2,2,3,3,4,4,4-nonalfluoropotassium salt (CAS 29420-49-3).
Given 14% degradation after 28 days, the test item is not readily biodegradable according to OECD criteria.

Description of key information

The biodegradability of the test item was derived from the source substance 1-butanesulfonic acid, 1,1,2,2,3,3,4,4,4-nonalfluoropotassium salt (CAS 29420-49-3).

Given 14% degradation after 28 days, the test item is not readily biodegradable according to OECD criteria.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed
Type of water:
freshwater

Additional information