Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-182-0 | CAS number: -
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 February 2013 to 19 February 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The vapour pressure of the substance as a 50% w.w. concentration in pharmaceutical white oil has been determined to be 0.00015 Pa at 25°C.
- Executive summary:
The vapour pressure of the substance as a 50% w.w. concentration in pharmaceutical white oil has been determined to be 0.00015 Pa at 25°C.The vapour pressure of the test item was determined in a GLP-compliant vapour pressure balance test (Harlan 2013) following OECD guideline 104. The study is considered reliable and relevant for use for this endpoint.
Reference
A total of seven runs were completed for the main sequence. Equilibrium with regard to vapour pressure was assessed to have been reached over the final six runs. Thus, the final six runs have been used to calculate the definitive vapour pressure value for the test item. The values of vapour pressure at 25°C extrapolated from each graph are summarized in the following table:
Run |
Log10[Vp(25ºC)] |
2 |
-3.79 |
3 |
-3.82 |
4 |
-3.87 |
5 |
-3.79 |
6 |
-3.82 |
7 |
-3.85 |
Mean |
-3.82 |
Vapor Pressure |
1.50 x 10-4Pa |
The test item did not change in appearance under the conditions used in the determination.
Description of key information
The vapour pressure of the substance as a 50% w.w. concentration in pharmaceutical white oil has been determined to be 0.00015 Pa at 25°C.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
The vapour pressure of the test item was determined in a GLP-compliant vapour pressure balance test (Harlan 2013) following OECD guideline 104
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
