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Registration Dossier
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EC number: 236-757-0 | CAS number: 13475-82-6
Endpoint summary
Administrative data
Description of key information
There is data available for this substance. Additionally, key and supporting data is available for structural analogues. The data is read across to this substance based on analogue read across and a discussion and report on the read across strategy is provided as an attachment in IUCLID Section 13.
The substances are poorly soluble and made of constituents with various water solubility. As a consequence, the exposures were performed with Water Accommodated Fractions (WAFs). Therefore, the results are based on nominal loadings.
According to the harmonised CLP legislation (2008), Annex VI, this substance is classified for the environment as aquatic chronic category 4 with the hazard statement H413: May cause long lasting harmful effects to aquatic life.
Additional information
Key and supporting information is summarised below:
Short-term toxicity to fish
Hydrocarbons, C11-C13 (odd number), n-alkanes,<2% aromatics presented a 96-h LL50 (mortality) for Danio rerio of >100 mg/L (based on nominal concentration).
Hydrocarbons, C12-C15, n-alkanes, isoalkanes, <2% aromatics presented a 96-h LL50 (mortality) for Cyprinus carpio of >100 mg/L (water-accommodated fraction (WAF)).
Hydrocarbons, C9-C10, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 (mortality) for Oncorhynchus mykiss ranging from >10 to <30 mg/L (WAF).
Hydrocarbons, C9-C10, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of 50.9 mg/L (WAF).
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of >1,000 mg/L (WAF).
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of >1,000 mg/L (WAF).
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of >1,000 mg/L (WAF).
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of >792,000 mg/L (water-soluble fraction).
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of >803,000 mg/L (water-soluble fraction).
Hydrocarbons, C12-C16, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of >87,556 mg/L (WAF).
Hydrocarbons, C12 -C16, isoalkanes, cyclics, <2% aromatics, showed no mortality for Oncorhynchus mykkis at a loading of 788,000 mg/L during a 96 -hour exposure period
Isododecane produced a 96-hour LL50 value of >1 g/L and LL0 value of 1 g/L forBrachydanio rerio. Based on the measured concentrations, the 96-hour LC50 value was >2.8 ug/L and LC0 value was 2.8 ug/L.
Long-term toxicity to fish
The aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
Short-term toxicity to aquatic invertebrates
Hydrocarbons, C12-C15, n-alkanes, isoalkanes, <2% aromatics presented a 48-h EL50 for Daphnia magna of >100 mg/L (WAF) based on mobility.
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 48-h LL50 for Daphnia magna of >1,000 mg/L (WAF) based on mortality.
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 for Chaetogammarus marinus of >10,000 mg/L (WAF) based on mortality.
Decane presented a 96-h LL50 for Chaetogammarus marinus of >1,000 mg/L (WAF) based on mortality.
Decane presented a 96-h EL50 for Daphnia magna of >1,000 mg/L (WAF) based on mobility.
Decanepresented a 96-h LL50 for Mysidopsis bahia of >1,000 mg/L (WAF) based on mortality.
Undecane presented a 96-h LL50 for Chaetogammarus marinus of >1,000 mg/L (WAF) based on mortality.
Undecane presented a 96-h EL50 for Daphnia magna of >1,000 mg/L (WAF) based on mobility.
Undecane presented a 96-h LL50 for Mysidopsis bahia of >1,000 mg/L (WAF) based on mortality.
Hydrocarbons, C11-C14, n-alkanes, <2% aromatics presented a 48-h LL50 for Arcartia tonsa of >10,000 mg/L (WAF) based on mortality.
Dodecane presented a 96-h LL50 for Chaetogammarus marinus of >1,000 mg/L (WAF) based on mortality.
Dodecane presented a 96-h EL50 for Daphnia magna of >1,000 mg/L (WAF) based on mobility.
Dodecane presented a 96-h LL50 for Mysidopsis bahia of >1,000 mg/L (WAF) based on mortality.
Tridecane presented a 96-h LL50 for Chaetogammarus marinus of >1,000 mg/L (WAF) based on mortality.
Tridecane presented a 96-h EL50 for Daphnia magna of >1,000 mg/L (WAF) based on mobility.
Tridecane presented a 96-h LL50 for Mysidopsis bahia of >1,000 mg/L (WAF) based on mortality.
Tetradecane presented a 96 -h LL50 for Chaetogammarus marinus of >1,000 mg/L (WAF) based on mortality.
Tetradecane presented a 96-h EL50 for Daphnia magna of >1,000 mg/L (WAF) based on mobility.
Tetradecane presented a 96-h LL50 for Mysidopsis bahia of >1,000 mg/L (WAF) based on mortality.
Hydrocarbons, C12-C16, isoalkanes, cyclics, <2% aromatics presented a 96-h LL50 forChaetogammarus marinus of >10,000 mg/L (WAF) based on mortality.
Hydrocarbons, C12 -C13, isoalkanes, cyclics, <2% aromatics presented a 48 -hour EL50 of > 81,300 mg/L and the 48-hour EC50 of > 1.3 mg/L for Dapnhia magna.
Isododecane (a 90% saturated solution) did not produce a 50% effect (immobility) withDaphnia magnaafter a 48-hour exposure. The saturated solution of test substance was developed by adding 1 g/L and using the filtered aqueous phase. Therefore, the 48-hour EL50 can ony be reported as >90% of a saturated solution of the test substance. Since the analytical results were below the limit of detection, 10 ug/L, the results cannot be quantified based on either a loading or concentration basis.
Long-term toxicity to aquatic invertebrates
Hydrocarbons, C11-C13 (odd number), n-alkanes,<2% aromatics presented a 21-d NOELRs for Daphnia magna of ≥ 10.2 mg/L (nominal loading rate), based on parent mortality and reproduction per surviving.
Hydrocarbons, C11-C13, isoalkanes, <2% aromatics presented a 21-d NOELRs for Daphnia magna of 1 mg/L (nominal loading rate), based on effects on survival, reproduction, or length.
Isododecane produced a 21-Day EL50 (immobilisation) value, based on nominal values, forDaphnia magnaof 0.029 mg/l. The 21-Day EL50 (reproduction) value based on nominal values was calculated as 0.045 mg/l.
Toxicity to algae and cyanobacteria
Hydrocarbons, C11-C13 (odd number), n-alkanes, <2% aromatics presented a 72-h EL50 (growth rate) for Pseudokirchneriella subcapitata of >100 mg/L (WAF) and a 72-h NOELR (growth rate) for Pseudokirchneriella subcapitata of ≥100 mg/L (WAF).
Hydrocarbons, C12-C15, n-alkanes, isoalkanes, <2% aromatics presented a 72-h EL50 (growth rate) for Pseudokirchneriella subcapitata of >100 mg/L (WAF) and a 72-h NOELR (growth rate) for Pseudokirchneriella subcapitata of 100 mg/L (WAF).
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 72-h EL50 (growth rate and biomass) for Skeletonema costatum of >100,000 mg/L (WAF) and a 72-h NOELR (growth rate and biomass) for Skeletonema costatum of 100,000 mg/L (WAF).
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 72-h EL50 (growth rate) for Skeletonema costatum of >100,137 mg/L (WAF) and a 72-h EL10 (growth rate) for Skeletonema costatum from 60021 to 80072 mg/L (WAF).
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 72-h EL50 (growth rate and biomass) for Pseudokirchneriella subcapitata of >1,000 mg/L (WAF) and a 72-h NOELR (growth rate and biomass) for Pseudokirchneriella subcapitata of 1,000 mg/L (WAF).
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 72-h EL50 (growth rate and biomass) for Pseudokirchneriella subcapitata of >1,000 mg/L (WAF) and a 72-h NOELR (growth rate and biomass) for Pseudokirchneriella subcapitata of 1,000 mg/L (WAF).
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics presented a 72-h EL50 (growth rate and biomass) for Pseudokirchneriella subcapitata of >1,000 mg/L (WAF) and a 72-h NOELR (growth rate and biomass) for Pseudokirchneriella subcapitata of 1,000 mg/L (WAF).
Isododecane, presented a 72-hr EC10, EC50, and EC90 values for the two endpoints are all reported as >22.5 ug/L. The 72-hr NOEC values for biomass and growth rate are both reported as 22.5 ug/L for Desmodesmus subspicatus.
Toxicity to microorganisms
Hydrocarbons, C11-C13 (odd number), n-alkanes, <2% aromatics presented a 3-h EC10 (respiration inhibition) for activated sludge of >1,000 mg/L.
Isododecane presented a 5-h EC50 (respiration rate inhibition) for Pseudomonas putida of >2 mL/L.
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