Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-620-1 | CAS number: 108-83-8
Endpoint summary
Administrative data
Description of key information
Additional information
Acute toxicity data were available for fish, Daphnia and algae. Acute endpoints included an LC50 of 30 mg/L for rainbow trout (96- hr), 37.2 mg/L (48 -hr) for Daphnids and 49.7 mg/L (72 -hr growth inhibition) with algae. These values fall between 10 - 100 mg/L which indicates that diisobutyle ketone is only slight toxic to aquatic organisms.
This aliphatic ketone has a low log Kow of 3.71, a predicted BCF value of 130 L/kg and is readily biodegradable. Diisobutyl ketone s is expected to be effectively removed during activated sludge sewage treatment and is not expected to occupy the water, sediment or soil compartments. The risk assessment shows that the PEC/PNEC ratio is clearly <1, indicating no need for further information or testing. According to REACH Annex IX requirements, long-term toxicity testing shall only be considered when the chemical safety assessment indicates the need for further investigation. Therefore, long-term testing in aquatic species (fish and daphnid) can be waived for diisobutyl ketone.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
