Registration Dossier

Toxicological information

Respiratory sensitisation

Currently viewing:

Administrative data

Endpoint:
respiratory sensitisation
Remarks:
no data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original source document not reviewed. Information from a secondary source included for completion.

Data source

Reference
Reference Type:
publication
Title:
Aerosolized acetaldehyde, but not ethanol, induces histamine mediated brochoconstriction in guinea pigs
Author:
Myou, S., Fujimura, M., Bando, T., Saito, M., Matsuda, T.
Year:
1994
Bibliographic source:
Clin Exp Allergy, 24, 140-3

Materials and methods

Test guideline
Deviations:
not specified
Principles of method if other than guideline:
No further information available.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No further information available

Test animals

Species:
guinea pig
Strain:
Hartley
Sex:
male

Test system

Route of induction exposure:
inhalation
Vehicle:
other: 0.9% saline
Concentration:
31, 62,5, 125, 250mM

No. of animals per dose:
No data.
Positive control substance(s):
not specified
Negative control substance(s):
not specified

Results and discussion

Results:
No data.
Positive control results:
No data.
Negative control results:
No data.

Any other information on results incl. tables

Ethanol did not cause bronchorestriction.

Applicant's summary and conclusion

Interpretation of results:
no data