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Environmental fate & pathways

Biodegradation in water and sediment: simulation tests

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Endpoint:
biodegradation in water: sewage treatment simulation testing
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Remarks:
The study was well documented and meets generally accepted scientific principles, but was not conducted in compliance with GLP.
Principles of method if other than guideline:
other: 14C-sewage treatment plant simulation test

GLP compliance:
no
Radiolabelling:
yes
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic, adapted
Initial conc.:
1.3 mg/L
Based on:
other: active substance
Parameter followed for biodegradation estimation:
radiochem. meas.
% Degr.:
0.3
Parameter:
radiochem. meas.
Remarks:
14CO2 evolution
Sampling time:
14 wk
Transformation products:
not measured
Conclusions:
poorly biodegradable under pertaining test conditions
Endpoint:
biodegradation in water: sewage treatment simulation testing
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Remarks:
The study was well documented and meets generally accepted scientific principles, but was not conducted in compliance with GLP.
Principles of method if other than guideline:
Method: other: Screening Test / radioactive substance
GLP compliance:
no
Radiolabelling:
yes
Oxygen conditions:
aerobic
Inoculum or test system:
other: adapted inoculum
Initial conc.:
0.3 mg/L
% Degr.:
3.5
Parameter:
radiochem. meas.
Remarks:
14CO2 evolution
Sampling time:
70 d
Remarks on result:
other: after pre-adaption
Transformation products:
not measured

not significantly biodegradable

Conclusions:
other: poorly biodegradable under pertaining test conditions

Description of key information

A number of simulation studies are available and provide a consistent weight of evidence for a lack of significant biodegradation under STP and aquatic simulation conditions in the absence of other factors.

Although biodegradation in sediment has not been demonstrated for HEDP-H and its salts, the role of abiotic removal processes is significant. The key data for sediment adsorption are from the study by Michael (undated) (refer to Section 5.4.1 for further information about this test). There is no evidence for desorption occurring. Effectively irreversible binding is entirely consistent with the known behaviour of complexation and binding within crystal lattices. The high levels of adsorption which occur are therefore a form of removal from the environment. After approximately 40-50 days, the phosphonate is >95% bound to sediment with only 5% extractable by ultrasonication and use of 0.25N HCl-xylene solvent (based on radiolabelling) in river and lake water microcosms (Monsanto internal report, cited by Gledhill and Feijtel, 1992). 66-80% removal (binding) is seen after 11 days in the same test. In the context of the exposure assessment, largely irreversible binding is interpreted as a removal process; 5% remaining after 40 - 50 days is equivalent to a half-life of 10 days which is significant for the environmental exposure assessment on the regional and continental scales. This abiotic removal rate is used in the chemical safety assessment of HEDP-H and its salts.

Key value for chemical safety assessment

Half-life in freshwater:
10 d
at the temperature of:
12 °C
Half-life in freshwater sediment:
10 d
at the temperature of:
12 °C

Additional information