Registration Dossier
Registration Dossier
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EC number: 468-710-7 | CAS number: 754-12-1
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 117 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- O2 consumption
- Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- < 5
- Sampling time:
- 28 d
- Results with reference substance:
- Sodium benzoate (the reference substance) attained a maximum level of biodegradation (based on the BOD:ThOD ratio) of 83%.
The results obtained from the toxicity control bottles showed the test substance did not inhibit the biodegradation of sodium benzoate, as the mean oxygen consumption in the toxicity control bottles was similar to the total of the mean oxygen consumptions by the two separate components. - Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
Reference
Description of key information
Under aerobic conditions < 5% biodegradation of HFO-1234yf was observed after 28 days
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
HFO-1234yf is not found readily biodegradable after 28 days under aerobic conditions.
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