Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 212-344-0 | CAS number: 793-24-8
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
A test with the homolgue substance 7PPD caused a statistically significant reduction in the nitrate formation in soil at concentrations of 333 mg/kg soil dry weight and above.
At test-item concentrations of 10.0 mg/kg soil dw and 100 mg/kg soil dw nitrate concentration in soil was statistically significantly increased.
The LOEC and NOEC were determined to be 333 mg/kg soil dw and 100 mg/kg soil dw, respectively. Due to the lacking of a dose-response relationship effective concentrations (ECx) could not be calculated.
Based on the above results, the test item, 7PPD is considered to have no adverse long-term effects on nitrate formation in soil at concentrations up to and including 100 mg test item/kg soil dry weight.
Key value for chemical safety assessment
- Long-term EC10 or NOEC for soil microorganisms:
- 100 mg/kg soil dw
Additional information
According to the OECD Guideline 216 (Soil Microorganisms: Nitrogen Transformation Test), he study was conducted in order to determine possible effects of 7PPD on soil microorganisms through measuring microbial nitrate formation in treated versus untreated soils after 28 days of incubation. A NOEC of 100 mg/L and a LOEC of 333 mg/L within 28 days related to nitrate formation.
7PPD is considered to have no adverse long-term effects on nitrate formation in soil at concentrations up to and including 100 mg test item/kg soil dry weight.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
