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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

Reference
Name:
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane
Type of composition:
boundary composition of the substance
State / form:
liquid
Reference substance:
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane
PBT status:
the substance is not PBT / vPvB
Justification:

The assessed substance, [3-(2,3-epoxypropoxy)propyl]silanetriol is the hydrolysis product of the submission substance.

[3-(2,3-epoxypropoxy)propyl]trimethoxysilane hydrolyses rapidly in contact with water to form [3-(2,3-epoxypropoxy)propyl]silanetriol and methanol.

 

The silanol hydrolysis product, [3-(2,3-epoxypropoxy)propyl]silanetriol may persist in the environment but does not meet the criteria for B or T, and therefore the hydrolysis product should not be concluded as PBT or vPvB.

There is a testing proposal to clarify the genetic toxicity potential for germ cells following a positive result in a comet assay.