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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Qualifier:
according to
Guideline:
other: OECD guideline for testing of chemicals - draft proposal - February 2001. Transformation dissolution of metals and metal compounds in aqueous media.
Qualifier:
according to
Guideline:
other: The standard operating procedure for the transformation/dissolution of metals and sparingly soluble metal compounds, version February 2004.
GLP compliance:
no
Remarks:
The tests were following as close as possible the GLP guidelines proposed by OECD
Type of method:
flask method
Water solubility:
18 µg/L
Temp.:
21.8 °C
pH:
6.11
Remarks on result:
other: Co2Et concentration at 0 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
141.6 µg/L
Temp.:
21.5 °C
pH:
6.08
Remarks on result:
other: Co2Et concentration at 24 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
126.3 µg/L
Temp.:
21.4 °C
pH:
6.1
Remarks on result:
other: Co2Et concentration at 48 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
144.1 µg/L
Temp.:
21.3 °C
pH:
6.08
Remarks on result:
other: Co2Et concentration at 96 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
134.5 µg/L
Temp.:
21.3 °C
pH:
6.08
Remarks on result:
other: Co2Et concentration at 168 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
127.7 µg/L
Temp.:
21.9 °C
pH:
5.94
Remarks on result:
other: Co2Et concentration at 672 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
379 µg/L
Temp.:
22.4 °C
pH:
6.06
Remarks on result:
other: CoZEt concentration at 0 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
1 549.8 µg/L
Temp.:
21.1 °C
pH:
6.14
Remarks on result:
other: Co2Et concentration at 24 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
1 454.4 µg/L
Temp.:
21.3 °C
pH:
6.01
Remarks on result:
other: Co2Et concentration at 48 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
1 405.1 µg/L
Temp.:
21.8 °C
pH:
5.84
Remarks on result:
other: Co2Et concentration at 168 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
261.1 µg/L
Temp.:
21.7 °C
pH:
6.6
Remarks on result:
other: Co2Et concentration at 0 hour sampling time at 100 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
14 300.2 µg/L
Temp.:
21.9 °C
pH:
6.69
Remarks on result:
other: Co2Et concentration at 168 hour sampling time at 100 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Conclusions:
Under the conditions of the transformation/dissolution test, the dissolution of Co2Et is 127.7 µg/L at 1 mg/L loading for the 28-day endpoint. The dissolution of Co2Et is 1405.1 µg/L at 10 mg/L loading for the 7-day endpoint.The dissolution of Co2Et is 14300.2 µg/L at 100 mg/L loading for the 7-day endpoint.
Executive summary:

A seven day transformation/dissolution test according to the OECD guideline 29 and the GHS (Annex 10) protocol was run on Co2Et at a mass loading of 10 and 100 mg/L, at a pH of 6.0. Also a 28 day transformation/dissolution was run on Co2Et at a mass loading of 1 mg/L and at a pH of 6.0. Under the conditions of this test, the dissolution of Co2Et is 127.7 µg/L for the 28 -day endpoint (1 mg/L loading), 1405.1 µg/L for the 7-day endpoint (10 mg/L loading) and 14300.2 µg/L for the 7-day endpoint (100 mg/L loading).

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008-09-14 to 2008-10-01
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
, 1995
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Water solubility:
40.3 g/L
Temp.:
20 °C
pH:
6.8
Details on results:
The water solubility of the test material has been determined to be 40.3g/L of solution, at 20.0 +/- 0.5°C. however, the visual findings suggest that the solubility may be inversely proportional to temperature.
Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)The water solubility of the test material has been determined to be 40.3g/L of solution, at 20.0 +/- 0.5°C. however, the visual findings suggest that the solubility may be inversely proportional to temperature.
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2008-09-08 to 2008-12-10
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study reliable with restrictionsi) no method validation was performed (ii) according to the results the test substance is depended on temperature, in this case it is necessary to perform the water solubility testing at 10°C as well
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
adopted 1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
, 1992
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Water solubility:
25 050 mg/L
Temp.:
20 °C
pH:
ca. 6.97
Water solubility:
6 300 mg/L
Temp.:
37 °C
pH:
>= 6.31 - <= 6.54
Details on results:
The water solubilities of cobalt 2-ethylhexanoate were determined to be 25.05 g/L at 20 °C (after 72 hours shaking) based on a measured concentration of 4.27 g Co/L (+/- 0.201 g Co/L) and 6.30 g/L at 37°C (after 72 hours shaking) based on a measured concentration of 1.07 g Co/L (+/- 0.201 g Co/L).
Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)The water solubilities of the test item cobalt 2-ethylhexanoate were determined to be 25.05 g/L at 20 °C based on a measured concentration of 4.27 g Co/L (+/- 0.201 g Co/L) and 6.30 g/L at 37°C based on a measured concentration of 1.07 g Co/L (+/- 0.201 g Co/L).

Description of key information

Water solubility of cobalt bis(2-ethylhexanoate) (flask method, guideline study results): 40.3 g/L at  20 °C.

Key value for chemical safety assessment

Water solubility:
40.3 g/L
at the temperature of:
20 °C

Additional information

Acc. to Walker et al. (2008) cobalt bis(2-ethylhexanoate) has a water solubility of 40.3 g/L at 20.0 °C. However, the visual findings suggest that the water solubility may be inversely proportional to temperature.

This observation is supported by a second experiment (Habeck, 2009), investigating the water solubility at 20 and 37°C. Hence, the water solubilities of cobalt bis(2-ethylhexanoate) were determined to be 25.05 g /L at 20 °C and 6.30 g/L at 37 °C.