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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 October 2011
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: according to ISO 13320:2009 “Particle size analysis – Laser diffraction methods
Qualifier:
according to
Guideline:
other: ISO 13320:2009 "Particle size analysis - Laser difraction methods"
Deviations:
no
Principles of method if other than guideline:
A sample of tantalum was dispersed in water, and passed through a laser. The light scattered by the particles at various angles was measured by multi-element detectors, and numerical values relating to the scattering pattern were recorded for subsequent analysis. The Fraunhofer approximation was used for calculation of the particle size distribution.
GLP compliance:
not specified
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Mass median aerodynamic diameter:
27.93 µm
Percentile:
D10
Mean:
5.58 µm
St. dev.:
0.56
Remarks on result:
other: According to ISO 13320 the relative standard deviation for d50 is smaller than 3 %, for d10 and d90 smaller than 5 %. For powders below 10 µm these maximum values should be doubled.
Percentile:
D50
Mean:
27.93 µm
St. dev.:
0.84
Remarks on result:
other: According to ISO 13320 the relative standard deviation for d50 is smaller than 3 %, for d10 and d90 smaller than 5 %. For powders below 10 µm these maximum values should be doubled.
Percentile:
D90
Mean:
41.11 µm
St. dev.:
2.06
Remarks on result:
other: According to ISO 13320 the relative standard deviation for d50 is smaller than 3 %, for d10 and d90 smaller than 5 %. For powders below 10 µm these maximum values should be doubled.

For a detailed report on the results, please see the attached.

Mean diameters (distribution type: volume) were determined by applying the Fraunhofer approximation.

Table 1: Distribution percentiles

Percentile (%)

Size (µm)

5.0

1.49

10.0

5.58

15.0

16.40

20.0

19.24

25.0

21.15

30.0

22.84

35.0

24.29

40.0

25.58

45.0

26.78

50.0

27.93

60.0

30.30

70.0

32.95

75.0

34.49

80.0

36.27

85.0

38.40

90.0

41.11

95.0

44.95

98.0

49.56

99.5

53.39

100.0

57.68

Conclusions:
Under the conditions of the study, the mean diameters (distribution type: volume) applying the Fraunhofer approximation were determined to be: D10 = 5.58 µm, D50 = 27.93 µm and D90 = 41.11 µm.
Executive summary:

The particle size of the test substance was determined according to ISO 13320:2009 "Particle size analysis - Laser diffraction methods". Under the conditions of the study, the mean diameters (distribution type: volume) applying the Fraunhofer approximation were determined to be: D10 = 5.58 µm, D50 = 27.93 µm and D90 = 41.11 µm.

Description of key information

D10 = 5.58 µm, D50 = 27.93 µm and D90 = 41.11 µm, ISO 13320:2009, Sunderkötter 2012.

Additional information

The particle size of the test substance was determined according to ISO 13320:2009 "Particle size analysis - Laser diffraction methods". Under the conditions of the study, the mean diameters (distribution type: volume) applying the Fraunhofer approximation were determined to be: D10 = 5.58 µm, D50 = 27.93 µm and D90 = 41.11 µm. The study was assigned a reliability score of 2 in accordance with the principles for assessing data quality as described in Klimisch (1997).