Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 201-116-6 | CAS number: 78-42-2
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient data documentation.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 958
Materials and methods
- Type of study / information:
- in vivo irritation study in human.
- Endpoint addressed:
- skin irritation / corrosion
- Principles of method if other than guideline:
- skin irritation study in human
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Tris(2-ethylhexyl) phosphate
- EC Number:
- 201-116-6
- EC Name:
- Tris(2-ethylhexyl) phosphate
- Cas Number:
- 78-42-2
- Molecular formula:
- C24H51O4P
- IUPAC Name:
- tris(2-ethylhexyl) phosphate
- Details on test material:
- no data
Constituent 1
Method
- Details on study design:
- no data
- Exposure assessment:
- not specified
Results and discussion
- Results:
- No irritant effects were seen after 24 h of exposure to a test substance-saturated cotton swab placed on the skin of the forearm of six volunteers. A piece (2 cm²) of PVC plastic containing 40% of test substance was placed on the arm of 8 volunteers for 72 h. Slight redness but no irritation was observed.
Any other information on results incl. tables
No irritant effects were seen after 24 h of exposure to a test substance-saturated cotton swab placed on the skin of the forearm of six volunteers. A piece (2 cm²) of PVC plastic containing 40% of test substance was placed on the arm of 8 volunteers for 72 h. Slight redness but no irritation was observed.
Applicant's summary and conclusion
- Executive summary:
No irritant effects were seen after 24 h of exposure to a test substance-saturated cotton swab placed on the skin of the forearm of six volunteers. A piece (2 cm²) of PVC plastic containing 40% of test substance was placed on the arm of 8 volunteers for 72 h. Slight redness but no irritation was observed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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