Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

No macroscopic cutaneous reactions attributable to allergy were recorded during the examination with guinea pigs after intradermal injection and topical administration.


Migrated from Short description of key information:
No macroscopic cutaneous reactions attributable to allergy, no cutaneous intolerance reactions observed.
No indication for an inhalative sensitization is given.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Based on an observation of 33 male employers at an average age of 48.3 a and an average period of employment of 15.1 a, no indication for an inhalative sensitization due to handling with the substance dust is given.


Migrated from Short description of key information:
No signs for reductions of the pulmonary function, no indication for an inhalative sensitization due to the inhalation of product dust.

Justification for classification or non-classification

Since there is no indication for inhalative sensitization due to handling with the substance, no reason for a classification is given.