Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Fish

The acute toxicity of Benzenediamine, ar-methyl-, polymer with 2-methyloxirane and oxirane to Fish (Danio rerio) was tested according to EU method C.1 'Acute toxicity for Fish' (2008). No toxic effects against Fish was observed during 96 hours exposure at a limit test concentration of 100 mg/L (Currenta, 2009).

Aquatic invertebrates

There are two studies that can both be used to provide the EC50 for toxicity against aquatic invertebrates. Both studies assessed the acute toxicity of Benzenediamine, ar-methyl-, polymer with 2-methyloxirane and oxirane according to OECD 202 and EU method C.2 ' acute toxicity for Daphnia' (2008). In both studies no toxic effects against D. magna was observed during 48 hours exposure at a limit test concentration of 100 mg/L (Currenta, 2009 and BASF, 2009). Thus, the EC50 of Benzenediamine, ar-methyl-, polymer with 2-methyloxirane and oxirane is > 100 mg/L.

The 21 day-EC10 of the structurally related substance ortho-Toluenediamine, propoxylated in a OECD 211 guideline study is 2.5 mg/l (nominal) for reproduction.

Algae

The acute toxicity of Benzenediamine, ar-methyl-, polymer with 2-methyloxirane and oxirane to Alga (Desmodesmus subspicatus former name: Scenedesmus subspicatus) was tested according to EU method C.3 'Alga, Inhibition test' (2009). During 72 hours exposure an ErC50 of 280.9 mg/L and EC10 of 63.4 mg/L was estimated (Currenta, 2009).

STP

The potential toxic effect of Benzenediamine, ar-methyl-, polymer with 2-methyloxirane and oxirane was tested according to EU method C.11, which is equal to OECD Guideline 209. Up to the highest nominal concentration of 1000 mg/L tested, Benzenediamine, ar-methyl-, polymer with 2-methyloxirane and oxirane showed 2.0% respiration inhibition on activated sludge within 3 hours (Currenta, 2009).

Read-across statement

No-Longer-Polymer (NLP) polyether polyols are produced by the reaction of various starter molecules with propylene oxide and/or ethylene oxide. These substances exhibit a remarkable uniformity in the physical/chemical properties which influence their fate and distribution in the environment. All NLP polyols have a full acute aquatic ecotoxicity dataset and do not exhibit acute toxicity below 100 mg/L. However, differentiation in chronic invertebrate toxicity is apparent and is based on the alcohol- or amino- starter molecules used to prepare these NLP polyols. A sub-grouping based on (i) aliphatic alcohol and amine NLP polyols, (ii) EDA- (ethylenediamine) based amino NLP polyols and (iii) o-TDA- (ortho­diaminotoluene) based aromatic NLP polyols is justified (ISOPA, 2010) and toxicity is expected to be similar between substances within each of these categories. It is considered appropriate to use ‘read-across’ of data of structural analogues within each sub-grouping to fill data gaps for chronic invertebrate toxicity and derive PNECs for endpoints based on these sub-groupings