Registration Dossier
Registration Dossier
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EC number: 242-367-1 | CAS number: 18480-07-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
No sensitization study is available on Strontium hydroxide itself and no study was performed due to the corrosive properties of the substance. However, an analogue approach is used for the read-across of sensitization properties of strontium hydroxide from strontium chloride, based on the hypothesis that properties are likely to be similar as a result of the presence of a common metal ion Sr2+. Further information on the read-across justification is included as attachment in Section 13.
Since Strontium chloride did not induce any skin sensitization effect in the guinea pig, Strontium hydroxide is not expected to have any sensitising potential.
Justification for classification or non-classification
Skin sensitisation:
Based on read-across from strontium chloride and according to the EC Regulation No. 1272/2008 and subsequent regulations, Strontium hydroxide is also not classified as skin sensitizer.
Respiratory sensitisation:
During long-year industrial practice, no cases of hypersensitivity were observed till now by workers exposed exclusively to strontium hydroxide. Thus, no classification as respiratory sensitiser according to regulation (EC) 1272/2008 is required.
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