Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2007-05-03
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: guideline study

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Physical state: solid
- Analytical purity: > 98% GC purity
- Purity test date: 2007-05-03
- Lot/batch No.: 561058
- Storage condition of test material: room temperature

Study design

Analytical method:
gas chromatography
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-1.1
Temp.:
20 °C
pH:
3.4
Details on results:
pH in water phase

Any other information on results incl. tables

Flask

Water phase

n-octanol phase

1:1

1.289 mg/ml

0.090 mg/ml

1:2

1.182 mg/ml

0.083 mg/ml

2:1

1.311 mg/ml

0.103 mg/ml

Flask

Log Pow

1:1

1.15

:2

1.15

2:1

1.10

Applicant's summary and conclusion

Conclusions:
Log Pow: -1.1 at 20 °C
Executive summary:

Log Pow: -1.1 at 20 °C