Registration Dossier

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010-01-19
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
Version / remarks:
Titration method
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name: 2,2-bis(hydroxymethyl)propionic acid
- Physical state: solid
- Analytical purity: > 98% GC purity
- Purity test date: 2007-05-03
- Lot/batch No.: 581017
- Storage condition of test material: room temperature

Results and discussion

Dissociating properties:
yes
Dissosciation constant
No.:
#1
pKa:
4.68
Temp.:
20 °C

Applicant's summary and conclusion

Conclusions:
pKa: 4.68 at 20°C
Executive summary:

pKa: 4.68 at 20°C