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Toxicity to soil macroorganisms except arthropods

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Toxicity to soil macroorganisms except arthropods:
Conclusion: Results from a 14-day earthworm toxicity study show that DIDP, an analog to DIUP, does not cause toxicity at high soil concentrations as determined in natural and artificial soils. Results from a 56-day earthworm reproduction study show that DINP, an analog to DIUP, does not cause reproductive toxicity at high soil concentrations as determined in an artificial soil. Based on the data, DIUP is not expected to be chronically toxic to earthworms.

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The results of short-term and long-term soil macro-organism toxicity studies are reported as EC50and NOEC values. The NOEC values from these studies represent the highest concentrations tested and measured under the conditions of the studies.

I5 Summary

The toxicity of di-isodecyl phthalate ester (DIDP), an analog to DIUP, as measured by mortality to the earthworm (Eisenia fetida) was evaluated in a 14-day study using natural and artificial soils.  No significant mortality was observed in natural and artificial soils dosed with DIDP after 14 days at a nominal loading rate of 10,000 mg/kg soil (dw), which measured 7,664 mg/kg natural soil (dw) and 8,435 mg/kg artificial soil (dw) (concentrations are from analyses of soils at test initiation). The toxicity of di-isononyl phthalate ester (DINP), an analog to DIUP, as measured by reproduction to the earthworm (Eisenia fetida) was evaluated in a 56 day study using an artificial soil. DINP did not effect earthworm (Eisenia fetida) reproduction, based on a 56-day limit study in artificial soil at a high measured concentration of 982.4 mg/kg soil (dw).

Because DINP, DIDP, and DIUP are structurally similar and exhibit the same biological activity, these data support the conclusion that DIUP would not cause toxicity to earthworms at high soil loading levels and also not effect earthworm reproduction.