Registration Dossier

Administrative data

Description of key information

The tests of Acute oral toxicity and Acute dermal toxicity were performed according to the following methods: 
Method B.1 tris: Acute Oral Toxicity - Acute Toxic Class Method, Council Regulation (EC) No.440/2008, published in O.J. L 142, 2008
Method B.3 Acute Toxicity (Dermal), Council Regulation (EC) No.440/2008, published in O.J. L 142, 2008
Both: GLP study
The inhalation study was not performed, the exposure is supposed to be insignificant.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
2 000 mg/kg bw

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
2 000 mg/kg bw

Additional information

From the results of both acute toxicity studies (oral and dermal) follows that the substance could not be classified as hazard substance.

LD50 > 2000 mg/kg bw (oral)

LD50 > 2000 mg/kg bw (dermal)

 

Justification for classification or non-classification

According to the results of the studies, the value of LD50 (oral and dermal) of the test substance - Tar, brown-coal, low-temp. - for rats of both sexes is higher than 2000 mg/kg of body weight (Rosslerova Z., 2010a, b).

The test substance - Tar, brown-coal, low-temp.is classified as Asp. Tox. 1; H304 May be fatal if swallowed and enters airways - according to Regulation (EC) No 1272/2008 criteria based on its physical and chemical properties (hydrocarbon, kinematic viscosity ≤ 20.5mm²/s at 40°C) and is not classified as Xn; R65 Harmful: may cause lung damage if swallowed according to Directive No. 67/548/EEC (kinematic viscosity > 7x10-6m2/s at 40°C).