Registration Dossier
Registration Dossier
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EC number: 222-079-2 | CAS number: 3338-24-7
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to Read Across Statement attached in Section 13
- Reason / purpose for cross-reference:
- read-across source
- Transformation products:
- not specified
- % Recovery:
- > 96.4 - < 101
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 120 h
- % Recovery:
- > 94 - < 98.6
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 120 h
- % Recovery:
- > 103 - <= 104
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 120 h
- Key result
- pH:
- 4
- Temp.:
- 25 °C
- DT50:
- > 1 yr
- Type:
- not specified
- Remarks on result:
- other: Estimated from results at 50°C
- Key result
- pH:
- 7
- Temp.:
- 25 °C
- DT50:
- > 1 yr
- Type:
- not specified
- Remarks on result:
- other: Estimated from results at 50°C
- Key result
- pH:
- 9
- Temp.:
- 25 °C
- DT50:
- > 1 yr
- Type:
- not specified
- Remarks on result:
- other: Estimated from results at 50°C
- Validity criteria fulfilled:
- yes
- Remarks:
- For all: Linearity of detector response/concentration in the range of 0.10-1.0 mg/L. For pH: second-order behavier. At pH 7 & 9: First-order behavior with correlation coefficents (r2) ≥ 0.998
- Conclusions:
- The test item was found not to hydrolyse neither at pH 4; 7 nor 9. The half-life is expected to be greater than 1 year at 25 ºC.
Remark: the test solution contains NaOH due to the production method. - Executive summary:
The test was performed according to the OECD guideline 111 under GLP compliance. The test item was found not to hydrolyse neither at pH 4; 7 nor 9. The half-life is expected to be greater than 1 year at 25 ºC.
Reference
Description of key information
The source substance was found not to hydrolyse at neither pH 4; 7 nor 9. The half-life is expected to be greater than 1 year at 25 ºC.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
