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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

The 90-day LOEL for Tilapia is 2.18 mg/L, due to pH effects. However, the study is considered to be unreliable. Overall, a lactate related hazard regarding long-term toxicity to fish is not identified. Since dilactide undergoes immediate hydrolysis in contact with water, forming lactic acid, this is the moiety of interest by read-across.

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Additional information

Lactic acid is a ubiquitous and essential molecule of life in all vertebrates. It is highly soluble in water, and will not (significantly) accumulate in water. Accordingly, a long-term effect in water for fish is likely to be due to physical effects (pH, electrostatic) at the gill membrane, rather than to systemic toxicity. Since dilactide undergoes immediate hydrolysis in contact with water, forming lactic acid, this is the moiety of interest by read-across.