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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009-09-04 to 2009-12-07
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Version / remarks:
27 July 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
- Name of test material (as cited in study report): LL Lactide
- Batch no: 0902000694
- Appearance: white flakes, solid
- Purity: 100 %
- Expiration date of the lot/batch: 2010-02-10
- Stability under storage conditions: stable
- Storage: at room temperature in the dark
Key result
Boiling pt.:
266 °C
Atm. press.:
1 019 hPa
Remarks on result:
other: Some polymerization occurred during boiling
Conclusions:
In conclusion, it can be stated that the boiling point of LL Lactide is 266 °C at atmospheric pressure.
Executive summary:

The boiling temperature of the test substance was determined using differential scanning calorimetry (DSC) in an experimental study conducted according to OECD TG 103. This technique records the difference in heat flow to two crucibles, one filled with test substance and the other filled with an inert reference material, while these crucibles are subjected to a controlled temperature programme. When the test substance undergoes a transition, such as melting or evaporation, it is indicated by a deviation from the base line of the heat-flow record. Because melting and evaporation are processes in which heat is consumed, for these processes the deviation from the base line is in the endothermic direction. The melting temperature or boiling temperature (if any) of the test substance is evaluated from the DSC curve as the extrapolated onset temperature of the endothermic melting or evaporation peak.

The boiling temperature of the test substance calculated as the mean value of experiments 1 and 2 is 266 °C at 101.9 +/- 0.1 kPa.

Description of key information

It can be stated that the boiling point of LL Lactide is 266 °C at atmospheric pressure based on the results from an experimental study conducted according to OECD TG 103.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
266 °C

Additional information