Registration Dossier
Registration Dossier
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EC number: 939-424-4 | CAS number: 1469983-44-5
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
NOEC 21 d Daphnia magna (OECD 211): > 4.83 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 4.83 mg/L
Additional information
All validity criteria were met.
10 Daphnia were exposed to the test item for each treatment and blank control for 21 days in a semi-static test system.
The offspring of the animals was counted each working day. Reproduction of the daphnia in the highest treatment was higher than in the blank control.
The content of the test item in the test solutions was determined using GC-MS determination. The analysis of the test item concentrations in the treatments showed a low correlation with the nominal concentrations because of the limited solubility in test medium. Therefore, the determination of the results was based on the geometric mean of the measured concentrations.
According to the OECD guideline, the offspring of dead animals must be taken into account if the death is caused by toxicity of the test item. Only inadvertent and/or accidental parental mortality should be excluded from evaluation. Because no toxicity could be observed, the offspring of deceased parent animals was excluded from the calculation of total offspring per treatment.
No observations were made which might cause doubts concerning the validity of the study outcome.
The result of the test is considered valid.
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