Registration Dossier
Registration Dossier
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EC number: 211-479-2 | CAS number: 650-51-1
Endpoint summary
Administrative data
Description of key information
Skin irritation/corrosion: Key study: Sodium trichloroacetate has shown potential of slight irritation for the rabbits skin, and the effects were fully reversible within 7 days. Test method was according to OECD guideline 404.
Eye irritation: Key study: Sodium trichloroacetate has shown extremelly irritant for the rabbits eyes. Test method was according to OECD guideline 405.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Skin irritation/corrosion:
Key study: Experimental result: Test method was according to OECD guideline 404. Sodium trichloroacetate has shown potential of slight irritation for the rabbits skin, and the effects were fully reversible within 7 days. Based on the results observed in the skin irritation study the substance is not classified as a skin irritant.
Eye irritation:
Key study: Experimental result: Test method was according to OECD guideline 405. Sodium trichloroacetate has shown extremelly irritant for the rabbits eyes. Based on the results observed in the eye irritation study, the mean scores for 24-72 h for eye irritation are 2.67, 2 and 1 for cornea opacity, conjunctiva redness and iris score, respectively. The observed damages are fully reversible within 14 days. Based on the CLP Regulation, the substance is classified as "Eye irritation Category 2".
Effects on eye irritation: irritating
Effects on respiratory irritation: irritating
Justification for classification or non-classification
Based on the results observed in the skin irritation study the substance is not classified as a skin irritant.
Based on the results observed in the eye irritation study, the mean scores for 24-72 h for eye irritation are 2.67, 2 and 1 for cornea opacity, conjunctiva redness and iris score, respectively. The observed damages are fully reversible within 14 days. Based on the CLP Regulation, the substance is classified as "Eye irritation Category 2".
Based on the list of harmonised classification and labelling, the substance is classified as STOT SE Category 3, H335: May cause respiratory irritation.
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