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The stability of the substance towards hydrolysis was determined (Bayer, 1999a). Based on kinetic parameters, the following dissipation half-lives were derived:

pH 4 (25 °C): t1/2: 529.88 h (extrapolation)

pH 4 (50 °C): t1/2: 34.92 h

pH 7 (50 °C): t1/2: 1.48 h

pH 9 (50 °C): t1/2: 0.98 h

The assumption that the ester functions were hydrolysed was proven by LC-MS. It could be shown that up to two ester functions within one molecule were cleaved by hydrolysis forming carboxylic acid functions. No further analysis was performed to determine the exact identity of the hydrolysis products.

Using the van´t Hoff´s rule the dissipation half-lives at 25°C for pH 7 and pH 9 were calculated:

pH 7 (25°C): t1/2: 7.89 h

pH 9 (25°C): t1/2: 5.21 h