α,α-bis[4-(dimethylamino)phenyl]-4-(phenylamino)naphthalene-1-methanol

Endpoint summary

Description of key information

Under normal conditions of use and exposure, there is limited possibility of the chemical Solvent Blue 4 entering into the living system and being bio-accumulative.

Key value for chemical safety assessment

Bioaccumulation potential:

no bioaccumulation potential

Additional information

Details on absorption

The absorption capacity of α,α-bis[4-(dimethylamino)phenyl]-4-(phenylamino)naphthalene-1-methanol (Solvent Blue 4) through the oral, inhalation and derma route is low given the use of the chemical mostly in the preparation of inks, toner s and pigments. Though dermal absorption and inhalation of the particulates is a possibility (given the nature of use); it is unlikely that the chemical will penetrate the skin and enter inside the living system. However, entry into the respiratory tract in the absence of use of protective masks is a possiblity.

Details on dostribution in tissues

Since α,α-bis[4-(dimethylamino)phenyl]-4-(phenylamino)naphthalene-1-methanol (Solvent Blue 4) has poor/moderate water solubility compared toits solubility in organic solvents; distribution to the various parts of the body through blood will be less significant compared to distribution through lipids.

Details on excretion

The chemical α,α-bis[4-(dimethylamino)phenyl]-4-(phenylamino)naphthalene-1-methanol (Solvent Blue 4) has a molecular weight range of 487.64. It is therefore expected that the excretion process through urine would be faster as the molecular weight of the substance is > 300 and this is a favourable value for excretion via the urine route. Also, given the greater solubility of the chemical in the lipds, some of the chemical is also likely to be excreted through the feaces or bile.