Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Short and long term toxicity to fish

One OECD 236 screening study is available which showed a 96h-LC50 of 11.3 mg/L (concentration corrected for instability over time as seen in the algae study). This result is supported by an acute fish result of an analogous substance (tert-butyl hydroperoxide, CAS 75-91-2). This substance has a 96h-LC50 for fish of 56.9 mg/L which is in the same order of magnitude as 1,1,3,3-Tetramethylbutyl hydroperoxide. The long-term toxicity to fish endpoint has been waived.

Short term toxicity to aquatic invertebrates

One OECD 202 GLP study with analytical monitoring is available which meets all the quality criteria. As the test substance did not remain stable during the test, the EC50 was calculated based on geometric mean values and the 48 h EC50 is 6.7 mg/L

Long term toxicity to aquatic invertebrates

One OECD 211 GLP study with analytical monitoring is available which meetins all the quality criteria. As the test substance did not remain stableduring the test, the effect values were calculated based on time weighted average concentrations. The 21d-EC10 for reproduction is 0.37 mg/L (TWA).

Toxicity to aquatic algae and cyanobacteria

One OECD 201 GLP study with analytical monitoring is available which meets all the quality criteria. As the test substance did not remain stable

during the test, the effect values were calculated based on geometric mean values and they are: ErC10 (72h) of 2.9 mg/L and ErC50 of 5.6 mg/L.

Toxicity to microorganisms

One OECD 209 study is available. The EC50 of 1,1,3,3-tetramethylbutyl hydroperoxide for activated sludge after 3 hours contact time is 138 mg/L with 95% confidence limits of 53 and 327 mg/L. The EC10 of 1,1,3,3-tetramethylbutyl hydroperoxide for activated sludge after 3 hours contact time is 33 mg/L with 95% confidence limits of 4 and 78 mg/L.

Additional information