Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.007 mg/L
Assessment factor:
50
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.006 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.74 µg/L
Assessment factor:
500
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
3.3 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
1.68 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.22 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.04 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Acute classification

The existing acute data [48 h EC50 Daphnia (6.7 mg/L); 72h ErC50 algae (5.6 mg/L)]. From an OECD 236 study and read cross results it is known that fish are least sensitive. As all effect values are above 1 mg/L, there is no acute classification for this substance.

Chronic classification

1,1,3,3-Tetramethylbutyl hydroperoxide is not readily biodegradable, and the measured log Kow is 2.9. The lowest chronic endpoint available is 21d EC10 for Daphnia reproduction (0.37 mg/L). When chronic data for less than 3 trophic levels are available the classification is assessed using both the existing chronic and acute data, and the most stringent outcome is chosen.

Based on chronic data (21d EC10 daphnia, 0.37 mg/L): Category Chronic 2

Based on acute data (48 h EC50 Daphnia, 5.6 mg/L): Category Chronic 2

Overall classification: Category Chronic 2