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Diss Factsheets
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EC number: 940-822-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
FAV-ES is a UVCB substance consisting of >30 constituents. The constituents typically are di- and triglycerides with fatty acid and di-acid side chains. The di-acid side chains are further esterified with n-butanol. The ester group therefore is the main recurring chemical functionality in these constituents.
Abiotic degradation / hydrolysis of the ester function is not expected to occur under environmentally relevant conditions. The biodegradation of FAV-ES is determined experimentally. FAV-ES was found to reach a degradation of 55.7% after 28 days, based on CO2 production (ultimate degradation). In order to further evaluate the outcome of the biodegradation test on FAV-ES, the biodegradability of each individual constituent in the UVCB is estimated using EpiSuite. The QSAR results demonstrate that all but one of the FAV-ES constituents are predicted to be readily biodegradable. The difference between the outcome of the QSAR model (all but one constituents readily biodegradable) and the actual biodegradation test (degradation observed, but not readily biodegradable), is related to the water solubility of the FAV-ES constituents. According to the QSAR results, the vast majority of the FAV-ES constituents has a water solubility below 10 µg/L. As a consequence, due to the relatively high substance loading in ready biodegradation tests, part of the test substance will not be dissolved, which slows down the degradation rate.
The estimated log Koc values show that 32 of the 34 identified constituents of FAV-ES have a log Koc value > 4. These relatively high Log Koc values indicate that the constituents of FAV-ES will have the tendency to distribute towards the soil and/or sediment compartment upon release into the environment.
The EpiSuite QSAR was used in order to gain information on the bioaccumulative potential of each of the identified constituents. The QSAR results show that 31 of the 34 constituents identified in FAV-ES have estimated BCF values < 2000. The remaining 3 constituents (F1, C4 and C5) have estimated BCF values of 2460, 2052 and 2802, respectively. Even though these estimated BCF values > 2000 indicate a potential for bioaccumulation, it has to be taken into account that the ester functions present in all FAV-ES constituents will be subject to hydrolysis under the influence of esterase and lipase enzymes present in the organism. As a consequence, an accumulation of the FAV-ES constituents in living organisms is unlikely. Therefore, none of the FAV-ES constituents are considered to have bioaccumulative potential.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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