Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 246-619-1 | CAS number: 25103-58-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of tert-dodecanethiol on green algae was tested according to OECD TG 201 using water accommodated fractions. Very few effects were observed with the series of concentrations between 0.3 and 100 mg/L WAFs. It was not possible to determine an EL50 or NOEC. As a weight of evidence approach based on the available information, the substance does not appear to be toxic to algae at or below the solubility limit.
Key value for chemical safety assessment
Additional information
The algal toxicity of tert-dodecanethiol was tested on green algae according to OECD TG 201. Due to poor solubility, composition (numerous isomers) and volatility of the substance, the study was carried out using water accommodated fractions, closed flasks together with a medium enriched in carbonates. Very few effects were observed with the series of concentrations between 0.3 and 100 mg/L WAFs. It was not possible to determine an EL50. Only a NOELR (growth rate) could be derived at 3.2 mg/L (nominal loading rate). However, as the flasks were opened at regular intervals throughout the study this test cannot be considered as valid. In this study, an EC50 of >100 mg/L was determined. This data was reviewed by Thomas & Comber (2013). As too little information was available on this study a Study Summary was not included in the IUCLID but publication is included in the attached document.
Taken as a weight of evidence approach based on the available information the substance does not appear to be toxic to algae at or below the solubility limit.
For this reason further attempts to perform studies on algae have been abandoned and the study is considered as waived on the basis of technical issues.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
