(1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

September 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Well documented study performed according to OECD 102 guideline and EU method A.1, under GLP and without deviation

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

2015-03-05

Type of method:

differential scanning calorimetry

Melting / freezing pt.:

< -20 °C

Atm. press.:

ca. 1 018.3 hPa

Decomposition:

no

Remarks:

No melting point is observed from -20°C

Remarks on result:

other: First determination

Melting / freezing pt.:

< -20 °C

Atm. press.:

ca. 1 025.5 hPa

Decomposition:

no

Remarks:

No melting point is observed from -20°C

Remarks on result:

other: Second determination

Key result

Melting / freezing pt.:

< -20 °C

Remarks on result:

other: Final value

Pre-study:

Peaks assigned to the boiling of the substance were observed and measurement was stopped at 550°C.

Temperatures corresponding to these peaks were used to create the following temperature program:

 

Temperature program:

Step	Initial temperature (°C)	Final Temperature (°C)	Heating rate (°C/min)	Duration (min)	Furnace atmosphere	Rate* (mL/min)	Liquid nitrogen cooling
1	20	-120	10	14	He	60	YES
2	-120	-120	0	5	He	60	NO
3	-120	210	10	40	He	60	NO

*Gas injection rate in the furnace.

First Determination:

Mass taken: 11.01 mg

  

Results  

No Melting point is observed from -20°C

Atmospheric pressure: 1018.3 hPa

Second Determination:

 

Mass taken: 13.32 mg

 

Results

No Melting point was observed from -20°C

Atmospheric pressure: 1025.5 hPa

Conclusions:

According to the OECD 102 guideline and the EU method A.1, no melting point of substance (-)-ALPHA-PINENE was observed from - 20°C.

Executive summary:

A study was performed to determine the melting point/range of test item (-)-alpha-pinene. The method used was Differential Scanning Calorimetry (DSC) and the test was according to Regulation EC No. 440/2008 Method A.1 and OECD Test Guideline 102 , "Melting Point/Melting Range".

In this method, two crucibles were put in the apparatus furnace under inert atmosphere (helium) at atmospheric pressure. One crucible contained the test item, the other was empty and considered as the reference. A specific temperature program was applied. Heat flow differences between the two crucibles and mass variation were recorded on a thermogram.

Two trials were conducted and corresponding thermograms were obtained, giving us the following results:

Trial	Melting point/range	Ambient pressure
1	< -20 °C	1018.3 hPa
2	< -20 °C	1025.5 hPa

The melting point of reference substance Indium respects the checking cards limits(156.6°C for a reference value of 156.6°C) so as its enthalpy (27.55 J/g for a reference value of 28.6 J/g). Therefore, this study is considered as valid.

No melting point of substance (-)-alpha-pinene was observed from - 20°C. Therefore, the melting point of the substance is < -20°C.

Description of key information

Melting point of substance (-)-alpha-pinene is < -20°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

-20 °C

Additional information

Key study conducted according to the OECD 102 Guideline and the EU A.1 method, under GLP without deviation and with certificate of analysis included. Therefore, a reliability of 1 is assigned and the result of this key study is proposed as the end point value.

This result is supported by consistent experimental data obtained with alpha-pinene multiconstituent.