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EC number: 211-448-3 | CAS number: 645-62-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study, with acceptable restrictions (e.g. non-GLP, no analytical verification of test item concentrations).
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: German Standard DIN 38412, Part 9
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-ethylhex-2-enal
- EC Number:
- 211-448-3
- EC Name:
- 2-ethylhex-2-enal
- Cas Number:
- 645-62-5
- Molecular formula:
- C8H14O
- IUPAC Name:
- 2-ethylhex-2-enal
- Details on test material:
- - Name of test material (as cited in study report): 2-Ethylhexen-2-al
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
- Details on test organisms:
- TEST ORGANISM
- Common name: Scenedesmus subspicatus (renamed to Desmodesmus subspicatus)
- Strain: SAG 86.81
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
Test conditions
- Test temperature:
- 20 °C
- Nominal and measured concentrations:
- Nominal test concentrations: 0 (control), 3.91, 7.81, 15.63, 31.25, 62.5, 125, 250 mg/l
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 20 ml glass tubes with flat bottom, plugged with siliconesponge caps, 10 ml test volume
- Fill volume: 100 ml
- Initial cells density: 10000 cells/ml
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 2 blanks per concentration (w/o cells)
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: according to DIN 38412, part 9; OECD medium
OTHER TEST CONDITIONS
- Photoperiod: continuous white light
- Light intensity and quality: 220/70 µEinstein above/below the test vessels
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
- Chlorophyll measurement: in vivo chlorophyll-a-fluorescence at 685 nm wavelength (as measure for cell number): after 0, 24, 48 72, and 96 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 62.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 125 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- 9.25 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC20
- Effect conc.:
- 13.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 27.71 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Any other information on results incl. tables
RS-Freetext:
The following nominal effect concentrations related to yield
(EyC), growth rate (ErC), and biomass integral (EbC) were
recalculated according to OECD TG 201 (adopted 23 Mar 2006)
using the fluorescence values for inhibition of biomass from
the original report. Since no calibration curve data were
available, fluorescence data were equated with cell numbers
(95 % confidence intervals in brackets):
Yield (mg/l)
------------------
72 h 96 h
EyC10: 5.71 (5.11-6.26) 6.95 (5.56-8.10)
EyC20: 7.61 (7.00-8.18) 8.95 (7.60-10.06)
EyC50: 13.17 (12.48-13.90) 14.49 (13.26-15.82)
NOEyC: 3.91 3.91
LOEyC: 7.81 7.81
Growth rate (mg/l)
------------------
72 h 72 h
ErC10: 9.25 (6.38-11.62) 10.83 (4.72-15.68)
ErC20: 13.50 (10.29-16.30) 15.41 (8.51-20.64)
ErC50: 27.71 (23.96-32.06) 30.18 (23.08-39.46)
NOErC: 62.50 62.50
LOErC: 125.00 125.00
Biomass integral (mg/l)
-----------------------
72 h 96 h
EbC10: 5.55 (4.73-6.30 6.23 (5.42-6.96)
EbC20: 7.54 (6.70-8.30 8.22 (7.40-8.96)
EbC50: 13.51 (12.62-14.47 13.92 (13.06-14.83)
NOEbC: 3.91 3.91
LOEbC: 7.81 7.81
Original effect values as given in the report
(nominal concentrations in mg/l):
72 h 96 h
EC20: 7.59 8.52
EC50: 13.8 15.3
EC90: 40.6 29.8
pH at test start (0 h) and at test end (72 h)
---------------------------------------------
stock solution (500 mg/l): pH 4.64 (conductivity: 15 µS/cm)
uninoculated inoculated
0 h 72 h 0 h 72 h
0 (control) 8.2 8.5 8.2 9.7
3.91 8.0 8.4 8.0 10.0
7.81 7.9 8.3 7.9 10.1
15.63 7.8 8.3 7.8 10.2
31.25 7.7 8.2 7.7 8.1
62.5 7.6 8.1 7.7 8.0
125 7.3 7.8 7.7 8.1
250 7.0 7.5 7.7 8.1
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.