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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2005
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
GLP compliance:
yes (incl. certificate)
Type of method:
electrical sensing zone (e.g. Coulter) method
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- batch No.of test material:
63630034
- Expiration date of the batch:
17.01.2007
- Purity test date: 96.4%


STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material:
At room temperature in the dark
Mass median aerodynamic diameter:
139.7 µm
Geometric standard deviation:
3.81
Key result
Percentile:
D95
Mean:
>= 7.43 - <= 1 410 µm
St. dev.:
3.81
Percentile:
D10
Mean:
< 16.13 µm
St. dev.:
3.81
Percentile:
D25
Mean:
< 49.26 µm
St. dev.:
3.81
Percentile:
D50
Mean:
< 139.7 µm
St. dev.:
3.81
Percentile:
D75
Mean:
< 275.9 µm
St. dev.:
3.81
Percentile:
D90
Mean:
< 425 µm
St. dev.:
3.81
Conclusions:
The test was conducted to BS ISO 13320-1 : 1999.
The D95 was determined in average between 7.3 and 1410  μm
Executive summary:

The test is conducted to determine the particle size distribution of Phytosphingosine. The sample is initially observed to determine whether sieving of the material is required. The final sample is then analysed using the Coulter Laser Diffraction Analyser fitted with a dry powder module. It is normal practice to complete 3 runs to ensure repeatability of results.

The test was conducted to BS ISO 13320-1 : 1999.

The D95 was determined in average between 7.3 and 1410  μm

Description of key information

The D95 was determined in average between 7.3 and 1410 μm.

Additional information