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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification

Data source

Reference
Reference Type:
other: prediction
Title:
QSAR prediction of cis diester
Author:
Gedeon Richter Plc.
Year:
2016
Bibliographic source:
QSAR Toolbox

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
NA

Test material

Constituent 1
Chemical structure
Reference substance name:
(-)-1β-2(2´-Diethoxy-carbonyl-ethyl)-1α-ethyl-1,2,3,4,6,7,12,12b-α-octahydro-indolo[2,3-a]quinolizin
EC Number:
603-912-2
Cas Number:
135266-72-7
Molecular formula:
C25H34N2O4
IUPAC Name:
(-)-1β-2(2´-Diethoxy-carbonyl-ethyl)-1α-ethyl-1,2,3,4,6,7,12,12b-α-octahydro-indolo[2,3-a]quinolizin

Results and discussion

% Degradation
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Value:
29
Remarks on result:
not readily biodegradable based on QSAR/QSPR prediction

Applicant's summary and conclusion

Interpretation of results:
not readily biodegradable