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Diss Factsheets
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EC number: 914-479-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Dissociation constant
Administrative data
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- August 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study (OECD TG 112).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
Test material
- Reference substance name:
- Montan waxes, type NaV 101
- IUPAC Name:
- Montan waxes, type NaV 101
- Details on test material:
- Test item. Licomont NaV 101
Constituent 1
Results and discussion
- Dissociating properties:
- not determined
Any other information on results incl. tables
Test Description
Before starting with the measurements described in the SOPs some solubility tests were performed.
Different volumes of water were added to different amounts of the test item and stirred for 48 h (see Table 1).
10 ml of several solvents were added each to approximately 4-5 mg of the test item and stirred for a while (see Table 1).
Results
Table 1 summarises the results of the solubility tests with water and organic solvents.
Table 1: Solubility tests in water and organic solvents
Amount of |
Solvent |
Amount of |
Observations |
9.79 |
Water |
100 |
Not dissolved |
9.82 |
Water |
500 |
Not dissolved |
9.33 |
Water |
1000 |
Not dissolved |
4-5 |
Methanol |
10 |
Not dissolved |
4-5 |
Acetonitrile |
10 |
Not dissolved |
4-5 |
Ethanol |
10 |
Not dissolved |
4-5 |
Acetone |
10 |
Not dissolved |
4-5 |
Toluene |
10 |
Not dissolved |
4-5 |
2-Propanol |
10 |
Not dissolved |
4-5 |
n-Heptan |
10 |
Not dissolved |
4-5 |
Xylene |
10 |
Not dissolved |
4-5 |
n-Decane |
10 |
Not dissolved |
4-5 |
n-Tetradecane |
10 |
Not dissolved |
4-5 |
2-Butanone |
10 |
Not dissolved |
4-5 |
1-Hexanol |
10 |
Not dissolved |
3 |
Propylene carbonate |
25 |
Not dissolved |
The solubility of the test item in water is <9.33 mg/L, in propylene carbonate <120 mg/L and in all other tested organic solvents <500 mg/L. No further solubility tests with lower amounts of the test item in the organic solvents were performed. Due to the fact that the test solutions for the determination of the dissociation constant can only contain 1% of a water miscible solvent, the concentration of the test item would be too low for detection either with the pH-electrode or with the UV-spectrometer. Due to the insolubility of the test item in water and organic solvents the determination of the dissociation constant could not be performed.
Applicant's summary and conclusion
- Conclusions:
- Due to the low solubility of the test item in water and in several organic solvents the dissociation constant pKa could not be determined according to the OECD Guideline 112 (Dissociation constants in water (1981)).
- Executive summary:
The objective of this study was the determination of the dissociation constant of the test item according to OECD Guideline 112, Dissociation constants in water (1981). Due to the low solubility of the test item in water and in organic solvents, the dissociation constant pKa could not be determined according to the OECD Guideline 112.
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