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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Diss Factsheets

Ecotoxicological information

Toxicity to terrestrial arthropods

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to non-target arthropods on inert substrate (NTA other than pollinators)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1983
Reliability:
2 (reliable with restrictions)
Qualifier:
no guideline available
Principles of method if other than guideline:
other
GLP compliance:
no
Application method:
other: water
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material:
Ammonium bromide is an inorganic salt that dissociates to its composite ions in aqueous solutions at environmental pH and temperature. Comparison of the available data on the various bromide salts have shown that the bromide ion is the relevant ion for determination of the toxicological profile with simple cations such as potassium, sodium or ammonium, that are ubiquitous in nature, having little or no influence on the bromide ion properties. It is therefore justified to read-across data from other inorganic bromide salts to ammonium bromide.
Analytical monitoring:
no
Details on sampling:
no further details
Vehicle:
not specified
Details on preparation and application of test substrate:
no further details
Test organisms (species):
Culex pipiens quinquefasciatus
Animal group:
Diptera (mosquitoe)
Details on test organisms:
Strain / Clone Culex pipiens (mosquito)
Source Standardised laboratory culture
Age 1st instar
Kind of food Puppy food, milk powder, blood
Study type:
laboratory study
Limit test:
yes
Total exposure duration:
25 d
Post exposure observation period:
no further details
Test temperature:
26-28 degree C
pH (if soil or dung study):
Not stated
Humidity:
Not stated
Photoperiod and lighting:
circadic
Details on test conditions:
Criteria Details
Test type Semistatic
Renewal of test solution Renewals performed every Monday, Wednesday and Friday
Volume of test vessels 50 mL
Volume/animal 1.7 mL per animal
Number of animals/vessel 30 animals per vessel
Number of vessels/ concentration 2
Test performed in closed vessels due to significant volatility of TS No
Nominal and measured concentrations:
Nominal concentrations used differed by a factor of √10. Test concentrations included 100 mg/L. Full range tested was not stated.
Reference substance (positive control):
no
Duration:
25 d
Dose descriptor:
LOEC
Effect conc.:
320 other: mg/L
Basis for effect:
other: mortality and development
Duration:
25 d
Dose descriptor:
NOEC
Effect conc.:
100 other: mg/L
Basis for effect:
other: mortality and development
Details on results:
no further details
Results with reference substance (positive control):
no further details
Reported statistics and error estimates:
Not stated

Test result is equivalent to: NOEC = 77.6 mg(Br-)/L for the bromide ion
Validity criteria fulfilled:
not specified
Conclusions:
Culex pipiens were exposed to sodium bromide (concentration range not specified) in test waters for 25 days in a semi-static toxicity test. Observations of mortality and development were used to determine the LOEC and NOEC values.
Individual sub lethal effects and mortality data were not given. The 25 day NOEC was found to be 100 mg/L NaBr based on both of the observation criteria, mortality and development.

Description of key information

Culex pipiens were exposed to sodium bromide in test waters for 25 days in a semi-static toxicity test. Observations of mortality and development were used to determine the LOEC and NOEC values. The 25 day NOEC was found to be 100 mg/L sodium bromide based on both of the observation criteria, mortality and development.

Key value for chemical safety assessment

Long-term EC10, LC10 or NOEC for soil dwelling arthropods:
100 mg/kg soil dw

Additional information

Ammonium bromide is an inorganic salt that dissociates to its composite ions in aqueous solutions at environmental pH and temperature. Comparison of the available data on the various bromide salts have shown that the bromide ion is the relevant ion for determination of the toxicological profile with simple cations such as potassium, sodium or ammonium, that are ubiquitous in nature, having little or no influence on the bromide ion properties. It is therefore justified to read-across data from other inorganic bromide salts to ammonium bromide.

Culex pipiens were exposed to sodium bromide in test waters for 25 days in a semi-static toxicity test. Observations of mortality and development were used to determine the LOEC and NOEC values. The 25 day NOEC was found to be 100 mg/L sodium bromide based on both of the observation criteria, mortality and development.