Προηγούμενες/Αποτελέσματα

Προηγούμενες/Αποτελέσματα

Προηγούμενες/Αποτελέσματα

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts 272-723-1 68909-93-3
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
Details
Allyl (cyclohexyloxy)acetate 272-657-3 68901-15-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/08/2018
10/08/2018
24/09/2018
24/09/2018
Details
Kieselguhr, soda ash flux-calcined 272-489-0 68855-54-9 Sub-chronic toxicity (90 day): inhalation 01/07/2011 15/08/2011 Details
Distillates (petroleum), full-range straight-run middle 272-341-5 68814-87-9 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Distillates (petroleum), heavy straight-run (EC 272-817-2) (CAS 68915-96-8) 21/01/2021 08/03/2021 Details
Distillates (petroleum), full-range straight-run middle 272-341-5 68814-87-9 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Phosphorodithioic acid, mixed O,O-bis(sec-Bu and 1,3-dimethylbutyl) esters, zinc salts 272-238-5 68784-31-6
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category"
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category"
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
Details
Phosphorodithioic acid, mixed O,O-bis(sec-Bu and 1,3-dimethylbutyl) esters, zinc salts 272-238-5 68784-31-6
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with another ZDDP read-across category member depending on the outcome of the other testing proposals
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (pre-natal developmental toxicity) 26/08/2021 11/10/2021 Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (two-generation reproductive toxicity) 02/02/2012 19/03/2012 Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (pre-natal developmental toxicity) 29/07/2011 12/09/2011 Details
Linseed oil, oxidized 272-038-8 68649-95-6 Genetic toxicity in vivo 01/07/2011 15/08/2011 Details
Linseed oil, oxidized 272-038-8 68649-95-6 Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
Resin acids and Rosin acids, hydrogenated, esters with triethylene glycol 271-996-4 68648-53-3
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Details
9-Octadecenoic acid (Z)-, sulfonated, potassium salts 271-843-1 68609-93-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
Details
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues 271-832-1 68609-68-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues 271-832-1 68609-68-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0 || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0. || Note: Testing proposal is based on concern identified by the registrant
19/10/2020
19/10/2020
03/12/2020
03/12/2020
Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2 Long-term toxicity to fish 18/02/2014 04/04/2014 Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2 Long-term toxicity to fish Sub-chronic toxicity (90-day): oral || Note: testing proposed with Reaction products of 1H-Imidazole- 1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0 29/02/2016 14/04/2016 Details
Carboxylic acids, di-, C4-6 271-678-5 68603-87-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with adipic acid (EC 204-673-3) 21/10/2021 07/12/2021 Details
Alkanes, C12-14-iso- 271-369-5 68551-19-9
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3) || Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3) || Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3) || Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8)
23/11/2020
23/11/2020
23/11/2020
07/01/2021
07/01/2021
07/01/2021
Details
Alkanes, C10-13-iso- 271-366-9 68551-17-7 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Dodecene, hydroformylation products, low-boiling 271-240-3 68526-92-1 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014 Details
Dodecene, hydroformylation products, low-boiling 271-240-3 68526-92-1 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017 Details
Dodecene, hydroformylation products, high boiling 271-239-8 68526-91-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
Details
Octene, hydroformylation products, high-boiling 271-237-7 68526-89-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
Details
Octene, hydroformylation products, high-boiling 271-237-7 68526-89-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
Alcohols, C11-14-iso-, C13-rich 271-235-6 68526-86-3 Reproductive toxicity (pre-natal developmental toxicity) 21/12/2021 04/02/2022 Details
Alcohols, C11-14-iso-, C13-rich 271-235-6 68526-86-3 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019 Details
ALCOHOLS, C11-14-ISO-, C13-RICH 271-235-6 68526-86-3 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016 Details
ALCOHOLS, C7-9-ISO-, C8-RICH 271-231-4 68526-83-0 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016 Details
Alkenes, C8-10, C9-rich 271-212-0 68526-55-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
25/06/2012
12/09/2011
12/09/2011
09/08/2012
Details
Naphtha (petroleum), steam-cracked middle arom. 271-138-9 68516-20-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)
Reproductive toxicity (pre-natal developmental toxicity) || Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)
Sub-chronic toxicity (90-day): oral || Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)
22/04/2021
22/04/2021
22/04/2021
07/06/2021
07/06/2021
07/06/2021
Details
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters 271-082-5 68515-40-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/06/2011
16/06/2011
01/08/2011
01/08/2011
Details
Resin acids and Rosin acids, esters with ethylene glycol 270-986-7 68512-65-2 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, ethylene glycol ester (CAS RN 68512-65-2) 02/07/2013 16/08/2013 Details
Phenol, methylstyrenated 270-966-8 68512-30-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
Diethylmethylbenzenediamine 270-877-4 68479-98-1 Long-term toxicity to fish 04/12/2023 18/01/2024 Details
Diethylmethylbenzenediamine 270-877-4 68479-98-1 Reproductive toxicity (pre-natal developmental toxicity) 29/07/2011 12/09/2011 Details
Boron, (benzenemethanamine)trifluoro-, (T-4)-, reaction products with Bu glycidyl ether 270-821-9 68478-46-6 Genetic toxicity in vivo 03/05/2023 19/06/2023 Details
Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction 270-728-3 68477-39-4
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7)
Reproductive toxicity (pre-natal developmental toxicity) || Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7)
Sub-chronic toxicity (90-day): oral || Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7)
22/04/2021
22/04/2021
22/04/2021
07/06/2021
07/06/2021
07/06/2021
Details
Fuels, diesel, no. 2 270-676-1 68476-34-6
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Details
Fuels, diesel, no. 2 270-676-1 68476-34-6 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Fuel oil, no. 4 270-673-5 68476-31-3 Reproductive toxicity (two-generation reproductive toxicity) 16/08/2011 30/09/2011 Details
Fuel oil, no. 4 270-673-5 68476-31-3
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum, (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Details
Fuel oil, no. 2 270-671-4 68476-30-2 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Fuel oil, no. 2 270-671-4 68476-30-2
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Details
Flue dust, portland cement 270-659-9 68475-76-3
Genetic toxicity in vivo
Sub-chronic toxicity (90 day): inhalation
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts 270-608-0 68457-79-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the substance, with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
Details
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts 270-608-0 68457-79-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/09/2016
01/09/2016
01/09/2016
17/10/2016
17/10/2016
17/10/2016
Details