Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Strontium chromate | 232-142-6 | 7789-06-2 | Long-term toxicity to fish | 31/05/2011 | 15/07/2011 | Details | |
dichloro(3-chloropropyl)methylsilane | 232-136-3 | 7787-93-1 | Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6, CAS 5089-70-3) | 16/10/2014 | 01/12/2014 | Details | |
(-)-pin-2(3)-ene | 232-077-3 | 7785-26-4 | Reproductive toxicity (pre-natal developmental toxicity) | 25/10/2017 | 11/12/2017 | Details | |
Multi-Wall Carbon Nanotubes, synthetic graphite in tubular shape | 231-955-3 | 7782-42-5 | Long-term toxicity to fish | 03/11/2011 | 19/12/2011 | Details | |
Silver nitrate | 231-853-9 | 7761-88-8 | Sub-chronic toxicity (90-day): oral | 16/06/2011 | 01/08/2011 | Details | |
Pentasodium triphosphate | 231-838-7 | 7758-29-4 | Sub-chronic toxicity (90-day) via the inhalatory route (rat) | 08/04/2010 | 24/05/2010 | Details | |
Barium sulfate | 231-784-4 | 7727-43-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride (EC 233-788-1) | 17/06/2020 | 03/08/2020 | Details | |
Barium sulfate | 231-784-4 | 7727-43-7 | Long-term toxicity to fish | 29/04/2011 | 14/06/2011 | Details | |
Potassium permanganate | 231-760-3 | 7722-64-7 | Reproductive toxicity (two-generation reproductive toxicity) | 14/02/2011 | 31/03/2011 | Details | |
N-(dimethylvinylsilyl)-1,1-dimethyl-1-vinylsilylamine | 231-701-1 | 7691-02-3 |
Reproductive toxicity (pre-natal developmental toxicity)
“|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)” Sub-chronic toxicity (90 day): inhalation
“|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)” |
12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 |
Details | |
Sodium phosphinate | 231-669-9 | 7681-53-0 | Reproductive toxicity (developmental toxicity) | 26/01/2011 | 14/03/2011 | Details | |
cobalt dichloride | 231-589-4 | 7646-79-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/07/2016 18/07/2016 |
01/09/2016 01/09/2016 |
|
Details |
Cobalt dichloride | 231-589-4 | 7646-79-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt dichloride | 231-589-4 | 7646-79-9 |
Carcinogenicity
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
COBALT DICHLORIDE | 231-589-4 | 7646-79-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
29/04/2016 29/04/2016 |
13/06/2016 13/06/2016 |
Details | |
Boron trifluoride | 231-569-5 | - | Genetic toxicity in vivo | 01/07/2011 | 15/08/2011 | Details | |
Pentaerythritol tetrakis(3-mercaptopropionate) | 231-472-8 | 7575-23-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
01/07/2011 01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 15/08/2011 |
Details | |
Pentaerythritol tetrakis(3-mercaptopropionate) | 231-472-8 | 7575-23-7 | Long-term toxicity to fish | 01/07/2021 | 16/08/2021 | Details | |
Sodium dihydrogenorthophosphate | 231-449-2 | 7558-80-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2016 | 17/10/2016 | Details | |
Sodium dihydrogenorthophosphate | 231-449-2 | 7558-80-7 | Sub-chronic toxicity (90-day): oral | 24/07/2019 | 09/09/2019 | Details | |
4-methylmorpholine 4-oxide, monohydrate | 231-391-8 | 7529-22-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/02/2015 16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 02/04/2015 |
Details | |
2-hydroxy-2-methylpropiophenone | 231-272-0 | 7473-98-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day) |
21/10/2019 15/03/2011 15/03/2011 15/03/2011 |
05/12/2019 29/04/2011 29/04/2011 29/04/2011 |
Details | |
Lithium chloride | 231-212-3 | 7447-41-8 | Genetic toxicity in vivo | 03/11/2023 | 18/12/2023 | Details | |
Lithium chloride | 231-212-3 | 7447-41-8 | Reproductive toxicity (two-generation reproductive toxicity) | 29/04/2011 | 14/06/2011 | Details | |
tellurium dioxide | 231-193-1 | 7446-07-3 | Sub-chronic toxicity (90-day): oral | 16/03/2015 | 30/04/2015 | Details | |
Dimethyl (p-methoxybenzylidene)malonate | 231-185-8 | 7443-25-6 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 23/03/2020 | 07/05/2020 | Details | |
Bismuth | 231-177-4 | 7440-69-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
Cobalt | 231-158-0 | 7440-48-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt | 231-158-0 | 7440-48-4 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Silver | 231-131-3 | 7440-22-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with silver(1+) acetate (CAS number 563-63-3) | 27/09/2017 | 13/11/2017 | Details | |
Silver | 231-131-3 | 7440-22-4 | Sub-chronic toxicity (90-day): oral | 29/04/2011 | 14/06/2011 | Details | |
Silicon | 231-130-8 | 7440-21-3 | Subchronic toxicity (90 day): inhalation | 14/02/2011 | 31/03/2011 | Details | |
Nickel | 231-111-4 | 7440-02-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2019 | 15/04/2019 | Details | |
Butyl glycollate | 230-991-7 | 7397-62-8 | Sub-chronic toxicity (90-day): oral | 15/04/2011 | 30/05/2011 | Details | |
Aluminum triformate | 230-898-1 | 7360-53-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity study (90-day): oral |
21/01/2011 21/01/2011 21/01/2011 |
07/03/2011 07/03/2011 07/03/2011 |
Details | |
tetrapotassium pyrophosphate | 230-785-7 | 7320-34-5 | Sub-chronic toxicity (90 day): inhalation | 01/07/2011 | 15/08/2011 | Details | |
Bis(2,3-epoxypropyl) terephthalate | 230-565-0 | 7195-44-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2012 16/05/2012 16/05/2012 |
02/07/2012 02/07/2012 02/07/2012 |
Details | |
2-(dimethylamino)-2-methylpropan-1-ol | 230-279-6 | 7005-47-2 | Reproductive toxicity (pre-natal developmental toxicity) | 31/01/2014 | 17/03/2014 | Details | |
Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) | 230-257-6 | 6990-43-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) | 230-257-6 | 6990-43-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
1-isopropyl-2,2-dimethyltrimethylene diisobutyrate | 229-934-9 | 6846-50-0 | Reproductive toxicity (pre-natal developmental toxicity) | 14/03/2016 | 28/04/2016 | Details | |
dimethoxydiphenylsilane | 229-929-1 | 6843-66-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
14H-benz[4,5]isoquino[2,1-a]perimidin-14-one | 229-904-5 | 6829-22-7 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
[3aR-(3aα,5aβ,9aα,9bβ)]-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan | 229-861-2 | 6790-58-5 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide | 229-782-3 | 6731-36-8 | Bioaccumulation aquatic / sediment | 25/06/2019 | 09/08/2019 | Details | |
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide | 229-782-3 | 6731-36-8 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2011 | 15/08/2011 | Details | |
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide | 229-782-3 | 6731-36-8 | Bioaccumulation aquatic / sediment | 01/04/2022 | 16/05/2022 | Details | |
N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine | 229-761-9 | 6711-48-4 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with N,N-diethylpropane-1,3-diamine (EC no. 203-236-4) | 22/09/2022 | 07/11/2022 | Details | |
1,8-diazabicyclo[5.4.0]undec-7-ene | 229-713-7 | 6674-22-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
4-methylthiosemicarbazide | 229-563-2 | 6610-29-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
3,9-dicyclohex-3-enyl-2,4,8,10-tetraoxaspiro[5.5]undecane | 229-542-8 | 6600-31-3 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
Hydrogen [4-[[4-(diethylamino)phenyl][4-[ethyl[(3-sulphonatobenzyl)amino]-o-tolyl]methylene]-3-methylcyclohexa-2,5-dien-1-ylidene](ethyl)(3-sulphonatobenzyl)ammonium, sodium salt | 229-390-2 | 6505-30-2 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
Disodium 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxynaphthalene-2,7-disulphonate | 229-208-1 | 6428-31-5 | Genetic toxicity in vivo | 01/07/2021 | 16/08/2021 | Details | |
1,1`-(1,1-dimethyl-3-methylene-1,3-propanediyl)bisbenzene | 228-846-8 | 6362-80-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Sodium hydrogen-5-sulphoisophthalate | 228-845-2 | 6362-79-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 |
Details | |
Sodium hydrogen-5-sulphoisophthalate | 228-845-2 | 6362-79-4 | Genetic toxicity in vivo | 29/04/2014 | 13/06/2014 | Details | |
Hexyl salicylate | 228-408-6 | 6259-76-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | 6166-86-5 |
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9) Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9) |
04/10/2013 04/10/2013 |
18/11/2013 18/11/2013 |
Details | |
2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | 6166-86-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (EC 219-137-4) | 25/05/2020 | 09/07/2020 | Details | |
2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | 6166-86-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
|
Details |
(R)-p-mentha-1,8-diene | 227-813-5 | 5989-27-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
trichloro(hexadecyl)silane | 227-575-2 | 5894-60-0 |
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6) Sub-chronic toxicity (90-day): oral Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6) |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
N,N'-hexane-1,6-diylbis(hexahydro-2-oxo-1H-azepine-1-carboxamide) | 227-563-7 | 5888-87-9 | Genetic toxicity in vivo | 18/09/2014 | 03/11/2014 | Details | |
o-(p-isocyanatobenzyl)phenyl isocyanate | 227-534-9 | 5873-54-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
1,1,3,3-tetramethylbutyl hydroperoxide | 227-369-2 | 5809-08-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
dichlorocyclohexylmethylsilane | 226-956-0 | 5578-42-7 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0) | 16/03/2015 | 30/04/2015 | Details | |
2-ethylhexyl benzoate | 226-641-8 | 5444-75-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 |
Details | |
Guanidinium phosphate (1:1) | 226-551-9 | 5423-22-3 | Sub-chronic toxicity (90-day): oral | 16/05/2014 | 30/06/2014 | Details | |
Citral | 226-394-6 | 5392-40-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
4,4'-methylenedi-2,6-xylenol | 226-378-9 | 5384-21-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
Pentane-1,2-diol | 226-285-3 | 5343-92-0 | Sub-chronic toxicity (90-day): oral | 16/06/2011 | 01/08/2011 | Details | |
2-Octyldodecan-1-ol | 226-242-9 | 5333-42-6 | Reproductive toxicity (two-generation reproductive toxicity) | 05/04/2011 | 20/05/2011 | Details | |
Sulphamidic acid | 226-218-8 | 5329-14-6 | Reproductive toxicity (pre-natal developmental toxicity) | 25/11/2021 | 10/01/2022 | Details | |
Sulphamidic acid | 226-218-8 | 5329-14-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with ammonium sulphamate (pH consideration) | 23/04/2018 | 07/06/2018 | Details | |
Sulphamidic acid | 226-218-8 | 5329-14-6 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
14/02/2011 14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 31/03/2011 |
Details | |
4,4'-methylenebis[N-sec-butylaniline] | 226-122-6 | 5285-60-9 | Bioaccumulation aquatic / sediment | 27/01/2020 | 12/03/2020 | Details | |
octyltrichlorosilane | 226-112-1 | 5283-66-9 | Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) | 25/06/2015 | 10/08/2015 | Details | |
4-[3-(1-naphthylamino)propyl]morpholine | 226-033-2 | 5235-82-5 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
Etocrilene | 226-029-0 | 5232-99-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
24/02/2020 24/02/2020 |
09/04/2020 09/04/2020 |
Details | |
N-[3-(dimethylamino)propyl]methacrylamide | 226-002-3 | 5205-93-6 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2011 | 14/06/2011 | Details | |
5-ethyl-1,3-dioxane-5-methanol | 225-967-8 | 5187-23-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2014 31/01/2014 |
17/03/2014 17/03/2014 |
Details | |
5-ethyl-1,3-dioxane-5-methanol | 225-967-8 | 5187-23-5 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
03/10/2023 03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 17/11/2023 |
Details | |
(3-chloropropyl)triethoxysilane | 225-805-6 | 5089-70-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
N-isopropylhydroxylamine | 225-791-1 | 5080-22-8 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 |
Details | |
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline | 225-716-2 | 5026-74-4 |
Genetic toxicity in vivo || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Sub-chronic toxicity (90-day): oral || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline | 225-716-2 | 5026-74-4 |
Genetic toxicity in vivo || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Sub-chronic toxicity (90-day): oral || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
N-(3-aminopropyl)iminodiethanol | 225-642-0 | 4985-85-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
2,2-bis(hydroxymethyl)propionic acid // 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid | 225-306-3 | - |
Reproductive toxicity (pre-natal developmental toxicity study) Sub-chronic oral toxicity (90-day): oral |
05/04/2011 05/04/2011 |
20/05/2011 20/05/2011 |
Details | |
Octylphosphonic acid | 225-218-5 | 4724-48-5 | Reproductive toxicity (pre-natal developmental toxicity) | 16/05/2014 | 30/06/2014 | Details | |
Octylphosphonic acid | 225-218-5 | 4724-48-5 | Sub-chronic toxicity (90-day): oral | 03/04/2023 | 22/05/2023 | Details | |
2,2'-(cyclohexylimino)bisethanol | 224-809-5 | 4500-29-2 | Reproductive toxicity (pre-natal developmental toxicity) | 17/09/2019 | 01/11/2019 | Details | |
3-methylpentane-1,5-diol | 224-709-1 | 4457-71-0 | Long-term toxicity to fish | 01/03/2023 | 17/04/2023 | Details | |
3-trimethoxysilylpropane-1-thiol | 224-588-5 | 4420-74-0 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 3-(triethoxysilyl)propanethiol (EC 238-883-1)
|| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 3-(triethoxysilyl)propanethiol (EC 238-883-1)
|| Note: Testing proposal is based on concern identified by the registrant. |
23/11/2020 23/11/2020 |
07/01/2021 07/01/2021 |
Details | |
3-trimethoxysilylpropane-1-thiol | 224-588-5 | 4420-74-0 | Long-term toxicity to fish||Note: testing proposed with 3-Triethoxysilylpropane-1-thiol (EC no. 238-883-1) | 22/09/2022 | 07/11/2022 | Details | |
4-morpholinecarbaldehyde | 224-518-3 | 4394-85-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
4-morpholinecarbaldehyde | 224-518-3 | 4394-85-8 | Sub-chronic toxicity (90-day): oral | 04/04/2014 | 19/05/2014 | Details | |
2,2,4,4,6,8,8-heptamethylnonane | 224-506-8 | 4390-04-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with two substances in a grouping approach: Icosane (EC 204-015-1) and Hydrocarbons, C14-C19, iso-alkanes, cyclics; aromatics <2% (920-114-2) | 02/11/2018 | 17/12/2018 | Details | |
Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane | 224-506-8 | 4390-04-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) | 224-235-5 | 4259-15-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) | 224-235-5 | 4259-15-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |