Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| Reaction mass of Benzeneacetic acid, alpha-oxo-, 1,1'-(oxydi-2,1-ethanediyl) ester and Benzeneacetic acid, alpha-oxo-, 2-(2-hydroxyethoxy)ethyl ester | 442-300-8 | - | Sub-chronic toxicity (90-day): oral | 04/10/2013 | 18/11/2013 | Details | |
| Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form | 939-559-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 01/09/2017 | 16/10/2017 | Details | |
| Reaction mass of Amines, coco alkyl and β-Alanine, N-(2-carboxyethyl)-, N-coco alkyl derivs. and β-Alanine, N-coco alkyl derivs. | 915-790-0 | - | Sub-chronic toxicity (90-day): oral | 12/12/2014 | 26/01/2015 | Details | |
| Reaction mass of Amides, rape-oil, N-(hydroxyethyl), ethoxylated and Glycerol, ethoxylated | 932-164-2 | - |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
| Reaction mass of Alkenes C20-24 and Alkenes C24-28 | 931-746-3 | 93924-10-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
03/11/2011 03/11/2011 16/07/2012 |
19/12/2011 19/12/2011 30/08/2012 |
Details | |
| Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt | 939-513-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance Sub-chronic toxicity (90-day): oral Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
| Reaction mass of [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid and Phosphonic acid, P-[(tetrahydro-2-hydroxy-2-oxido-4H-1,4,2-oxazaphosphorin-4-yl)methyl]- | 911-811-2 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2015 17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 04/06/2015 |
Details | |
| Reaction mass of 6-Chloro-2-{4[ethyl(2-hydroxyethyl)amino]phenyl}-1-methylbenzo[cd]indolium hydroxide and 6-chloro-2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]-1-methylbenz[cd]indolium acetate | 946-378-9 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
| Reaction mass of 6-Amino-5-(4-substituted-sulfophenylazo)-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt and 6-Amino-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-5-[sulfo- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt | 445-040-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
| Reaction mass of 4-tert-butylphenyl diphenyl phosphate and bis(4-tert-butylphenyl) phenyl phosphate and triphenyl phosphate | 700-990-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/09/2022 | 07/11/2022 | Details | |
| Reaction mass of 4-tert-butylphenol and 1,3- phenylenedimethanamine and 2-({[3-(aminomethyl) benzyl]amino}methyl)-4-tert-butylphenol | 939-071-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 |
Details | |
| Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane | 915-748-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with (CAS 211519-85-6) Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with (CAS 211519-85-6) |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
| Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane | 915-748-1 | - | Sub-chronic toxicity (90-day): oral || Note: testing proposed with polysulfides, bis[3-(triethyoxysilyl)propyl (CAS No 211519-85-6) | 25/05/2020 | 09/07/2020 | Details | |
| Reaction mass of 4,4'-methylenediphenyl diisocyanate and o-(p-isocyanatobenzyl)phenyl isocyanate / methylene diphenyl diisocyanate | 905-806-4 | - | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
| Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl | 905-837-3 | - | Long-term toxicity to fish || Note: substance forms part of category; testing is also proposed with Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI), Octylamine and Hexamethylenediamine (EC no. 923-615-4) | 26/08/2021 | 11/10/2021 | Details | |
| Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
| Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
| Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - | Sub-chronic toxicity (90-day): oral | 21/12/2021 | 04/02/2022 | Details | |
| Reaction mass of 3-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde and 4-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde | 915-650-9 | - |
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 3-CYCLOHEXENE-1-CARBOXALDEHYDE MULTICONSTITUENT (EC no. 253-617-4) (EC no. 257-943-8) Sub-chronic toxicity (90-day): oral||Note: testing proposed with 3-CYCLOHEXENE-1-CARBOXALDEHYDE MULTICONSTITUENT (EC no. 253-617-4) (EC no. 257-943-8) |
04/09/2023 04/09/2023 |
19/10/2023 19/10/2023 |
Details | |
| Reaction mass of 3,5,6,6-tetramethyl-4-methyleneheptan-2-one and (E)-3,4,5,6,6-pentamethylhept-3-en-2-one | 946-245-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 06/06/2023 | 21/07/2023 | Details | |
| Reaction mass of 2-tert-butyl-4,6-dimethylphenol and 4-tert-butyl-2,5-dimethylphenol | 911-254-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/06/2011 | 01/08/2011 | Details | |
| Reaction mass of 2-methylpent-2-ene and diisopropyl ether | 906-484-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
29/07/2011 29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 12/09/2011 |
Details | |
| Reaction mass of 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol and propylidynetrimethanol | 904-153-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
| Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol | 938-572-7 | - | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
| Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol | 938-572-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/09/2018 06/09/2018 |
22/10/2018 22/10/2018 |
Details | |
| Reaction mass of 2-[[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]methyl]oxirane and 1,3-bis[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol and 1-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-3-[4-[[4-[3-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-2-hydroxy-propoxy]-3,5-dimethyl-phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol | 941-357-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
08/02/2017 08/02/2017 |
27/03/2017 27/03/2017 |
Details | |
| Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid | 940-877-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/03/2019 29/03/2019 |
13/05/2019 13/05/2019 |
Details | |
| Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol | 907-996-4 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) | 10/08/2018 | 24/09/2018 | Details | |
| Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol | 907-996-4 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) | 27/05/2019 | 11/07/2019 | Details | |
| Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol | 907-996-4 | - | Reproductive toxicity (pre-natal developmental toxicity) 1st and 2nd PNDTs: || Note: testing proposed with 2-92-92-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) | 27/01/2020 | 12/03/2020 | Details | |
| Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinonedimethylpropyl)anthraquinone | 915-623-1 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
| Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinone | 915-623-1 | - | Reproductive toxicity (pre-natal developmental toxicity) | 15/04/2014 | 30/05/2014 | Details | |
| Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinone | 915-623-1 | - |
Genetic toxicity in vivo Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
| Reaction mass of 2,7-Naphthalenedisulfonic acid, 5-amino-3-[[4-[2-[4-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl)azo]-2-sulfophenyl]ethenyl]-3-sulfophenyl]azo]-4-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:5) and 3,3'-[ethylenebis[(3-sulpho-p-phenylene)azo]]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:6) and 3,3'-[vinylenebis[(3-sulpho-p-phenylene)azo]]bis[6-amino-4-hydroxynaphthalene-2-sulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:4) | 916-899-6 | - | Sub-chronic toxicity (90-day): oral | 10/08/2018 | 24/09/2018 | Details | |
| Reaction mass of 2,6-Octadien-1-ol, 3,7-dimethyl-, (E) and 2,6-Octadien-1-ol, 3,7-dimethyl-, (Z)- | 906-125-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 |
Details | |
| Reaction mass of 2,5-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane and 2,6-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane | 411-280-2 | - | Genetic toxicity in vivo | 16/07/2012 | 30/08/2012 | Details | |
| Reaction mass of 2,5,8,11-tetraoxatridecan-13-ol and 2,5,8,11,14-pentaoxahexadecan-16-ol | 915-389-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC no. 203-962-1) | 01/04/2022 | 16/05/2022 | Details | |
| Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane | 911-381-6 | - | Long-term toxicity to fish || Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
| Reaction mass of 2,2'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxymethylene]}dioxirane and 1,3-bis{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol and 3,3'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxy]}bis(1-{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol) | 941-357-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
| Reaction mass of 2,2'-oxydibutane and 2-methylpropan-2-ol and butan-2-ol and 2,2'-oxydipropane | 903-919-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
29/07/2011 29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 12/09/2011 |
Details | |
| Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]- | 911-490-9 | - | Sub-chronic toxicity (90-day): oral | 27/05/2019 | 11/07/2019 | Details | |
| Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]- | 911-490-9 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
18/11/2014 18/11/2014 |
02/01/2015 02/01/2015 |
Details | |
| Reaction mass of 2,2',2''-nitrilotriethanol and disodium succinate and sodium acetate and sodium bromide | 905-908-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 |
Details | |
| Reaction mass of 1-phenyloctadecane-1,3-dione and phenylicosane-1,3-dione | 915-316-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
| Reaction mass of 1-methyl-4-(1-methylethylidene)cyclohexyl acetate and p-menth-1-en-8-yl acetate | 904-693-9 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 04/09/2023 | 19/10/2023 | Details | |
| Reaction mass of 1-chlorobut-2-ene and 3-chlorobut-1-ene | 908-820-9 | - | Genetic toxicity in vivo | 16/07/2012 | 30/08/2012 | Details | |
| Reaction mass of 1-[2-(2-aminobutoxy)ethoxy]but-2-ylamine and 1-({[2-(2-aminobutoxy)ethoxy]methyl}propoxy)but-2-ylamine | 447-920-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 21/05/2018 | 05/07/2018 | Details | |
| Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt | 939-650-3 | - | Sub-chronic toxicity (90-day): oral | 10/05/2022 | 27/06/2022 | Details | |
| Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt | 939-650-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
| Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane | 608-489-8 | - | Genetic toxicity in vivo | 03/02/2016 | 21/03/2016 | Details | |