Προηγούμενες/Αποτελέσματα

Προηγούμενες/Αποτελέσματα

Προηγούμενες/Αποτελέσματα

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Hydroxycyclohexyl phenyl ketone 213-426-9 947-19-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/09/2019 01/11/2019 Details
2,4,7,9-tetramethyl-4,7-decanediol 451-160-7 17913-76-7
Long-term toxicity to fish
"|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3)
Reproductive toxicity (pre-natal developmental toxicity)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Details
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with triethylenetetramine 500-290-3 103758-99-2
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1; EC 500-191-5)
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1; EC 500-191-5)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Details
tetrasodium 7-[(E)-2-[2-(carbamoylamino)-4-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}phenyl]diazen-1-yl]naphthalene-1,3,6-trisulfonate 474-870-9 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Details
2,2-bis[[(1-oxopentyl)oxy]methyl]propane-1,3-diyl divalerate 239-937-7 15834-04-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2019 05/12/2019 Details
2-(2-(2-methoxyethoxy)ethoxy)ethanol 203-962-1 112-35-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2019 05/12/2019 Details
2-(2-methoxyethoxy)ethanol 203-906-6 111-77-3 Reproductive toxicity (pre-natal developmental toxicity) 21/10/2019 05/12/2019 Details
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) 939-700-4 - Sub-chronic toxicity (90-day): oral 21/10/2019 05/12/2019 Details
Reaction mass of 2,2'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxymethylene]}dioxirane and 1,3-bis{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol and 3,3'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxy]}bis(1-{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol) 941-357-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2019 05/12/2019 Details
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether 926-564-6 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
21/10/2019
21/10/2019
05/12/2019
05/12/2019
Details
2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated 500-022-5 9014-85-1 Reproductive toxicity (pre-natal developmental toxicity)

|| Note: testing proposed with 2,4,7,9-Tetramethyl-5-decyne-4,7-diol (CAS number 126-86-3) ||
25/11/2019 09/01/2020 Details
2-hydroxy-3-propyl-2H-furan-5-one 821-451-7 78920-10-2 Genetic toxicity in vivo

|| Note: Testing proposal is based on concern identified by the registrant. ||
25/11/2019 09/01/2020 Details
Heptanal 203-898-4 111-71-7 Reproductive toxicity (extended one-generation reproductive toxicity study)

|| Note: testing proposed with Heptanoic acid (CAS No. 111-14-8)
25/11/2019 09/01/2020 Details
Hexaboron dizinc undecaoxide 235-804-2 12767-90-7 Genetic toxicity in vivo

|| Note: Testing proposal is based on concern identified by the registrant.
25/11/2019 09/01/2020 Details
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate 939-702-5 - Long-term toxicity to fish 25/11/2019 09/01/2020 Details
2,2'-(octylimino)bisethanol 239-555-0 15520-05-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/11/2019
25/11/2019
09/01/2020
09/01/2020
Details
3-[(3-{[(3-acetoxy-2,2-dimethylpropylidene)amino]methyl}-3,5,5-trimethylcyclohexyl)imino]-2,2-dimethylpropyl acetate 805-722-7 1064082-81-0 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 17/12/2019 31/01/2020 Details
isliFe - - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 17/12/2019 31/01/2020 Details
Sodium hydrogen N-(1-oxotetradecyl)-L-glutamate 253-981-4 38517-37-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with L-Glutamic acid, N-coco acyl derivs., disodium salts (CAS number: 68187-30-4; EC number: 269-085-1) || Note: Testing proposal is based on concern identified by the registrant. 17/12/2019 31/01/2020 Details
Reaction mass of dipotassium 2-(3,4-dimethyl-1H-pyrazol-1-yl) succinate and dipotassium 2-(4,5-dimethy-1H-pyrazol-1-yl) succinate 950-225-1 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8)
17/12/2019
17/12/2019
31/01/2020
31/01/2020
Details
1-imino-1H-isoindol-3-amine 222-426-8 3468-11-9 Genetic toxicity in vivo 27/01/2020 12/03/2020 Details
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity):
1st PNDT on the registered substance
2nd PNDT with the registered substance
// Note: Testing proposal for an EOGRTS proposed to be conducted with the analogue substance 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1, CAS 112-35-6)
27/01/2020 12/03/2020 Details
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride 253-781-7 38103-06-9 Sub-chronic toxicity (90-day): oral 27/01/2020 12/03/2020 Details
4,4'-methylenebis[N-sec-butylaniline] 226-122-6 5285-60-9 Bioaccumulation aquatic / sediment 27/01/2020 12/03/2020 Details
4-chloroformylphthalic anhydride 214-874-8 1204-28-0 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020 12/03/2020 Details
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate 220-482-8 2781-11-5 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020 12/03/2020 Details
Ethylenediamine, salt with phosphoric acid 238-914-9 14852-17-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 27/01/2020 12/03/2020 Details
m-phenylene di(acetate) 203-596-2 108-58-7 Genetic toxicity in vivo 27/01/2020 12/03/2020 Details
N,N,N',N'-tetrakis(2,3-epoxypropyl)-m-xylene-α,α'-diamine 264-438-6 63738-22-7 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020 12/03/2020 Details
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol 907-996-4 - Reproductive toxicity (pre-natal developmental toxicity)
1st and 2nd PNDTs: || Note: testing proposed with 2-92-92-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)
27/01/2020 12/03/2020 Details
Tetramethylammonium hydroxide 200-882-9 75-59-2 Sub-chronic toxicity (90-day): oral
// Note: testing proposed with Tetramethylammonium chloride (EC 200-880-8)
|| Note: Link to justification in the registration dossier not given as the information is confidential
27/01/2020 12/03/2020 Details
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol 264-261-4 63469-23-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol 212-985-6 901-44-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
3-[[3-[[(2-cyanoethyl)amino]methyl]-3,5,5-trimethylcyclohexyl]amino]propiononitrile 300-496-1 93940-97-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
Diethyl ethylphosphonate 201-111-9 78-38-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
N,N'-diphenyl-p-phenylenediamine 200-806-4 74-31-7
Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
Reaction products of orthoboric acid with 2,2'-iminodiethanol (1:1) 701-083-2 -
Sub-chronic toxicity (90-day): oral “||Note: testing proposed with MEA Polyborate (EC 701-025-6)”
"Reproductive toxicity (pre-natal developmental toxicity)
“||Note: testing proposed with MEA Polyborate (EC 701-025-6)”
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
Sodium salts of [hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid (4-7 Na:1) 947-369-2 -
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1

|| Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1

|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
tetrahydro-2-methylfuran 202-507-4 96-47-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 260-829-0 57583-35-4
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Details
Poly(oxy-1,2-ethanediyl), α-butyl-ω-hydroxy- 500-012-0 9004-77-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1).
Reproductive toxicity (pre-natal developmental toxicity) – rats-
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)
Reproductive toxicity (pre-natal developmental toxicity) – rabbits
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Details
Reaction products of monoethanolamine and boric acid (1:1) 701-025-6 -
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Details
Reaction products of monoethanolamine and boric acid (1:3) 701-024-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Details
1,1'-(ethane-1,2-diyl)bis[pentabromobenzene] 284-366-9 84852-53-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 24/02/2020 09/04/2020 Details
1,4-phenylenebis[(4-phenoxyphenyl)methanone] 620-097-9 54299-17-1 Bioaccumulation test in Fish, Reproductive toxicity (pre-natal developmental toxicity) 24/02/2020 09/04/2020 Details
3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate 261-665-2 59219-71-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020 Details
4-tert-butylcyclohexyl acetate 250-954-9 32210-23-4 Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with cis-4-tert-butylcyclohexyl acetate
24/02/2020 09/04/2020 Details
Camphene 201-234-8 79-92-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020 Details
(1S)-1,5-anhydro-2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol 695-878-0 1283129-18-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Details
2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-α-D-glucopyranosyl bromide 686-241-8 81058-27-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Details