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Προηγούμενες/Αποτελέσματα

Προηγούμενες/Αποτελέσματα

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..) 943-172-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/05/2016
17/05/2016
17/05/2016
01/07/2016
01/07/2016
01/07/2016
Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol 939-719-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Reaction mass of cobalt and copper and iron 912-664-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Reaction mass of cobalt sulphide and nickel sulphide and trinickel disulphide 910-663-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Reaction mass of diisobutyl hydrogen phosphate and isobutyl dihydrogen phosphate 911-351-2 - Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Reaction mass of disodium hydroxysulfinatoacetate and disodium hydroxysulfonatoacetate - -
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity study (90-day): oral
13/12/2010
13/12/2010
27/01/2011
27/01/2011
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate 939-702-5 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethoxylated bisphenol A diacrylate
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Ethoxylated bisphenol A diacrylate
12/12/2014
12/12/2014
26/01/2015
26/01/2015
Reaction mass of hydrogenated and dehydrogenated rosin 911-238-8 -
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
19/07/2013
19/07/2013
02/09/2013
02/09/2013
Reaction mass of methyl dihydrogen phosphate and orthophosphoric acid and dimethyl hydrogen phosphate 908-996-7 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1).
Sub-chronic toxicity (90-day): oral || Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1).
20/05/2015
20/05/2015
06/07/2015
06/07/2015
Reaction mass of N,N,N',N'-tetrabutylmethylenediamine and dibutylamine 948-040-6 - Genetic toxicity in vivo || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: Testing proposal is based on concern identified by the registrant. 24/01/2019 11/03/2019
Reaction mass of N-[2-(2-oxoimidazolidin-1-yl)ethyl]methacrylamide and methacrylic acid 934-058-1 -
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
30/06/2014
Reaction mass of Octadecanamide, 12-hydroxy-N-[2-[(1-oxodecyl)amino]ethyl]- and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) and Decanamide, N,N'-1,2-ethanediylbis- 907-495-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity): in rat and rabbit
Sub-chronic toxicity (90 day): inhalation
27/05/2019
27/05/2019
27/05/2019
11/07/2019
11/07/2019
11/07/2019
Reaction mass of p-mentha-1,4-diene and p-mentha-1,3-diene and dipentene and p-mentha-1(7),2-diene and p-mentha-1,4(8)-diene 931-893-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Reaction mass of Poly(oxy-1,2-ethanediyl), ?-[2-[(2-hydroxyethyl)amino]-2-oxoethyl]-?-hydroxy-, mono-C13-15-alkyl ethers (odd numbered, branched and linear)-alkylethers, Acetamide, 2-(C13-15 (odd numbered, branched and linear)-alkyloxy)-N-(2-hydroxyethyl)- and Alcohols, C13-15-branched and linear - - Reproductive toxicity (pre-natal developmental toxicity) 16/08/2011 30/09/2011
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate 939-595-5 - Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015
Reaction mass of resin acids and rosin acids, hydrogenated, potassium salts and potassium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylate 915-657-7 -
Pre-natal developmental toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
Two-generation reproductive toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
19/07/2013
19/07/2013
02/09/2013
02/09/2013
Reaction mass of resin acids and rosin acids, hydrogenated, sodium salts and sodium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7- -isopropyl-1,4a-dimethylphenanthren-1-carboxylate 915-568-3 -
Pre-natal developmental toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
Two-generation reproductive toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
19/07/2013
19/07/2013
02/09/2013
02/08/2013
Reaction mass of Rosin, hydrogenated and [1R-(1a,4ß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylic acid 911-238-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid 939-201-1 - Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015
reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate 442-300-8 - Reproductive toxicity (pre-natal developmental toxicity) 15/01/2013 01/03/2013
Reaction product Formaldehyde, amine and phenol 476-290-1 - Genetic toxicity in vivo 15/08/2013 30/09/2013
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen 939-489-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Reaction product of Crude sludge and Calcium oxide. Crude sludge is the mixture of by-products of petroleum hydrocarbons refining (especially Total petroleum hydrocarbons, Polycyclic aromatic hydrocarbons, acid-refined heavy petroleum distillates). The Crude sludge is neutralised by calcium oxide in the ratio 80:20. The maturing process proceeds under ambient conditions and takes for at least 3 days. Subsequently, the reaction product is processed mechanically 930-592-4 - Reproductive toxicity (pre-natal developmental toxicity) 20/09/2013 04/11/2013
Reaction product of Distillates (petroleum), acid-treated heavy naphthenic and calcium oxide - - Reproductive toxicity (pre-natal developmental toxicity) 16/08/2011 30/09/2011
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda 939-368-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
17/06/2014
17/06/2014
01/08/2014
01/08/2014
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) 23/04/2018 07/06/2018
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid 938-645-3 -
Long-term toxicity to fish Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
Sub-chronic toxicity (90-day): oral Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
16/03/2015
16/03/2015
16/03/2015
30/04/2015
30/04/2015
30/04/2015
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid - -
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
16/08/2011
16/08/2011
30/09/2011
30/09/2011
30/09/2011
30/09/2011
Reaction products of 2-(4,6-bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-hydroxy phenol with ((C10-16, rich in C12-13 alkyloxy)methyl)oxyrane 410-560-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/01/2012
16/01/2012
01/03/2012
01/03/2012
Reaction Products of alcohols, C14-18, C18 unsat., esterified with phosphorus pentoxide and salted with amines, C12-14,-tert-alkyl 939-591-3 - Reproductive toxicity (pre-natal developmental toxicity) 15/04/2014 30/05/2014
Reaction products of di-, tri- and tetra-propoxylated propane-1,2-diol with ammonia 618-561-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Reaction products of Isophorone diamine, Butyl  glycidyl ether, and Bisphenol A diglicydyl ether - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Reaction products of pentaerythritol, propoxylated and 1-chloro-2,3-epoxypropane with hydrogen sulfide 701-196-7 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Reaction products of polyaminoalkane and substituted octadecanoic acid 434-430-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2016
16/12/2016
30/01/2017
30/01/2016
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide 939-459-5 - Sub-chronic toxicity (90-day): oral 30/11/2015 14/01/2016
Shale oils, heavy 930-690-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
17/11/2011
14/03/2016
14/03/2016
02/01/2012
28/04/2016
28/04/2016
Shale oils, light 923-592-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
17/11/2011
17/11/2011
17/11/2011
02/01/2012
02/01/2012
02/01/2012
Shale oils, light 923-592-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” 14/03/2016 28/04/2016
Slags, steelmaking, elec. furnace (stainless/high alloy steel production) 932-476-9 - Sub-chronic toxicity (90 day): inhalation 06/03/2012 20/04/2012
Sophorolipids: fermentation products of glucose and fatty acids, C18 (unsaturated), glycerol esters with yeast Candida Bombicola, partially hydrolysed 941-809-7 - Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. 24/07/2019 09/09/2019
Soybean oil, oligomerized 701-252-0 - Reproductive toxicity (pre-natal developmental toxicity) 06/09/2018 22/10/2018
Tetraammineplatinum (II) diacetate 457-310-8 - Genetic toxicity in vivo (COMET, OECD TG 489) || Note: Testing proposal is based on concern identified by the registrant. Testing proposed with Tetraammineplatinum dichloride (CAS 13933-32-9). 22/06/2017 07/08/2017
Trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide 700-597-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
18/06/2012
18/06/2012
02/08/2012
02/08/2012
Tri-C18-22 (even numbered)-alkyl 2-hydroxypropane-1,2,3-tricarboxylate 700-316-5 -
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-days): oral
11/01/2011
11/01/2011
25/02/2011
25/02/2011
Tris({[(hydroxyalkyl)amino]oxy}-oxoalkyl)-triazaalkanoic acid and water - - Reproductive toxicity (pre-natal developmental toxicity) 12/06/2013 29/07/2013
tri{[(2s)-1-ethoxy-1-oxopropan-2-yl]oxy}(vinyl)silane 701-301-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/05/2019
27/05/2019
11/07/2019
11/07/2019
Urea, N-octyl-N'-[4-[[4-[[(octylamino)carbonyl]amino]phenyl]methyl]phenyl]-Urea, N-[4-[[4[(octadecylamino)carbonyl]amino]phenyl]methyl]phenyl]-N’-octyl 445-760-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/07/2015
31/07/2015
14/09/2015
14/09/2015



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