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Diss Factsheets
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EC number: - | CAS number: 1474044-66-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Station Epuration Wavre 2nd stage, 26/09/2004
- Concentration of sludge:
- Initial cell/biomass concentration: >10,000,000 CFU/mL
- Water filtered: yes/no
- Type and size of filter used, if any: - Duration of test (contact time):
- 28 d
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium:standard medium used
- Additional substrate: no
- Test temperature: 21.4 - 20.8 deg C
- pH: 7.3 start/7.6 end
- pH adjusted: no
- Aeration of dilution water: yes
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparatus:3 L flasks mounted with an aeration tube on a magnetic stirrer.
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: CO2-free air passed through test system at 50-100 mL/min.
- Test performed in open system: yes
- Details of trap for CO2 : 100 mL flasks containing Ba(OH)2 solution. Every 2 days the flask closest to the test container is removed and back-titrated against HCl to determine the amount of CO2 released.
SAMPLING
- Sampling frequency: days 0, 2, 4, 7, 9, 11, 14, 16, 18, 21, 23, 25, 28, 29
- Sampling method: CO2 passed through a solution flask containing Ba(OH)2 where it precipitates as Ba(CO3)2. Remaining Ba(OH)2 is back titrated with HCl using phenolphthalein as indicator.
CONTROL AND BLANK SYSTEM
- Inoculum blank:
- Abiotic sterile control: No
- Toxicity control: Toxicity reference susbtance sodium benzoate at 20 mg C/L
STATISTICAL METHODS: None - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- 20 mg C/L
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 6.6
- Sampling time:
- 2 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 27.6
- Sampling time:
- 4 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 60.5
- Sampling time:
- 11 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 75
- Sampling time:
- 28 d
- Results with reference substance:
- 89.7 % degradation in 28-days
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Executive summary:
The substance is readily biodegradable - 75% degradation after 28 days, meeting 10 -day window (OECD TG 301B).
Reference
Blank control = 22.0 mg
Description of key information
The substance is readily biodegradable - 75% degradation after 28 days, meeting 10 -day window (OECD TG 301B).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
The ready biodegradability of the substance was tested in a study performed according to OECD TG 301B (CO2 evolution test). The substance achieved 75 % degradation after 28 days and reached 60.5 % within the 10 day window after exceeding 10 % degradation. On this basis, the substance is readily biodegradable.
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